Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 10/20 | 0.47 |
| ▸ | MAPK14 | Q16539 | 6/20 | 0.46 |
| ▸ | MAPK11 | Q15759 | 5/20 | 0.46 |
| ▸ | CSNK1E | P49674 | 7/20 | 0.46 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.46 |
| ▸ | CSNK1A1 | P48729 | 2/20 | 0.46 |
| ▸ | NUAK1 | O60285 | 1/20 | 0.46 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.46 |
| ▸ | LCK | P06239 | 1/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
| ▸ | MAP2K1 | Q02750 | 1/20 | 0.46 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.46 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.46 |
| ▸ | MAPK13 | O15264 | 3/20 | 0.44 |
| ▸ | MAPK12 | P53778 | 3/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.43 |
| ▸ | EGFR | P00533 | 1/20 | 0.43 |
| ▸ | FRK | P42685 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9933140 | 0.91 | CSNK1D (0.56) | CSNK1DMAPK14MAPK11CSNK1EMAP4K4 | |
| SCHEMBL9932611 | 0.81 | CSNK1D (0.55) | CSNK1DMAPK14MAPK11CSNK1EMAP4K4 | |
| SCHEMBL9933623 | 0.80 | CSNK1D (0.56) | CSNK1DMAPK14MAPK11CSNK1EMAP4K4 | |
| SCHEMBL9932288 | 0.74 | CSNK1D (0.50) | CSNK1DMAPK14MAPK11CSNK1EMAP4K4 | |
| SCHEMBL9961415 | 0.71 | CSNK1D (0.48) | CSNK1DMAPK14MAPK11CSNK1EMAP4K4 | |
| SCHEMBL3258489 | 0.70 | MAP4K4 (0.53) | CSNK1DMAPK14MAPK11CSNK1EMAP4K4 | |
| SCHEMBL30944216 | 0.70 | CSNK1D (0.36) | CSNK1DMAPK14MAPK11CSNK1EMAP4K4 | |
| SCHEMBL14411171 | 0.69 | CSNK1D (0.64) | CSNK1DMAPK14MAPK11CSNK1EMAP4K4 | |
| SCHEMBL985600 | 0.67 | ERBB2 (0.56) | MAPK14GSK3BMAP2K1AURKBERBB2 | |
| SCHEMBL9934171 | 0.67 | CSNK1D (0.68) | CSNK1DMAPK14MAPK11CSNK1EMAP4K4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012085721-A1 | NOVEL FUSED PYRIDINE COMPOUNDS AS CASEIN KINASE INHIBITORS | PFIZER INC. (US) | 2012-06-28 | — | — | WO | disclosed |