Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 20/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1016902 | 1.00 | EGFR (0.72) | EGFR | |
| SCHEMBL937832 | 0.95 | EGFR (0.80) | EGFR | |
| SCHEMBL13473565 | 0.95 | EGFR (0.68) | EGFR | |
| SCHEMBL937830 | 0.95 | EGFR (0.80) | EGFR | |
| SCHEMBL3613231 | 0.95 | EGFR (0.69) | EGFR | |
| SCHEMBL1020337 | 0.92 | EGFR (0.70) | EGFR | |
| SCHEMBL1020335 | 0.92 | EGFR (0.70) | EGFR | |
| SCHEMBL1019386 | 0.92 | EGFR (0.71) | EGFR | |
| SCHEMBL1019387 | 0.92 | EGFR (0.71) | EGFR | |
| SCHEMBL1015528 | 0.92 | EGFR (0.73) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2001890-B1 | TETRAHYDROPYRIDOTHIENOPYRIMIDINE COMPOUNDS AND USE FOR THE TREATMENT OF CELL PROLIFERATIVE DISORDERS | BAYER SCHERING PHARMA AG (DE) | 2011-01-12 | — | — | EP | disclosed |