⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3997444 | 1.00 | — | — | |
| SCHEMBL26015410 | 1.00 | — | — | |
| SCHEMBL18410021 | 0.78 | — | — | |
| SCHEMBL10169121 | 0.76 | — | — | |
| SCHEMBL836049 | 0.74 | — | — | |
| SCHEMBL519002 | 0.74 | — | — | |
| SCHEMBL433965 | 0.74 | — | — | |
| SCHEMBL16730992 | 0.72 | — | — | |
| SCHEMBL27820661 | 0.72 | — | — | |
| SCHEMBL25111573 | 0.70 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20220340893-A1 | BI-FUNCTIONAL COMPLEXES AND METHODS FOR MAKING AND USING SUCH COMPLEXES | NUEVOLUTION A/S (DK) | 2022-10-27 | — | — | US | disclosed |
| CN-110300754-A | Pyrrolo [1,2-b ] pyridazine derivatives | 吉利德科学公司 | 2019-10-01 | — | — | CN | disclosed |
| CN-110016020-A | Compound or pharmaceutically acceptable salt thereof, application and pharmaceutical composition thereof | 铁木医药有限公司 | 2019-07-16 | — | — | CN | disclosed |
| CN-107207515-B | Pyrazine compounds for the treatment of infectious diseases | 豪夫迈·罗氏有限公司 | 2019-05-28 | — | — | CN | disclosed |
| CN-105705501-B | ROR gamma modulators | 百时美施贵宝公司 | 2019-04-19 | — | — | CN | disclosed |
| CN-109384778-A | Use of a compound or a pharmaceutically acceptable salt thereof for the manufacture of a medicament for the treatment of a disease, health condition or disorder | 铁木医药有限公司 | 2019-02-26 | — | — | CN | disclosed |
| CN-109369635-A | Compound or pharmaceutically acceptable salt thereof, application and pharmaceutical composition thereof | 铁木医药有限公司 | 2019-02-22 | — | — | CN | disclosed |
| CN-109071563-A | Inhibitors of bruton's tyrosine kinase and methods of use thereof | 詹森药业有限公司 | 2018-12-21 | — | — | CN | disclosed |
| CN-108912111-A | compounds and pharmaceutical compositions | 铁木医药有限公司 | 2018-11-30 | — | — | CN | disclosed |
| CN-105408328-B | sGC stimulators | 铁木医药有限公司 | 2018-11-16 | — | — | CN | disclosed |
| CN-107207515-A | Pyrazine compounds for the treatment of infectious diseases | 豪夫迈·罗氏有限公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-105705501-A | Ror[Gamma] modulators | 百时美施贵宝公司 | 2016-06-22 | — | — | CN | disclosed |
| CN-103443107-B | Thiazolopyrimidine compound | F. HOFFMANN-LA ROCHE AG (CH) | 2016-04-20 | — | — | CN | disclosed |
| CN-105408328-A | sGC stimulators | IRONWOOD PHARMACEUTICALS INC | 2016-03-16 | — | — | CN | disclosed |
| CN-105143200-A | Serine/threonine kinase inhibitors for the treatment of hyperproliferative|diseases | ARRAY BIOPHARMA INC | 2015-12-09 | — | — | CN | disclosed |
| CN-103443107-A | Thiazolopyrimidine compounds | HOFFMANN LA ROCHE | 2013-12-11 | — | — | CN | disclosed |
| US-20120021530-A1 | HETEROGENEOUS FOLDAMERS CONTAINING alpha, beta, and/or gamma-AMINO ACIDS | WISCONSIN ALUMNI RESEARCH FOUNDATION | 2012-01-26 | — | — | US | disclosed |
| US-7858737-B2 | Heterogeneous foldamers containing α, β, and/or γ-amino acids | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2010-12-28 | — | — | US | disclosed |
| CN-1740150-A | 2-oxo-1-pyrrolidine derivatives, processes for preparing them and their uses | UCB SA (BE) | 2006-03-01 | — | — | CN | disclosed |
| CN-1404469-A | 2-oxo-1-pyrrolidine derivatives, preparation method and use thereof | UCB SA (BE) | 2003-03-19 | — | — | CN | disclosed |