Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 18/20 | 0.50 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | STS | P08842 | 2/20 | 0.43 |
| ▸ | UGT1A4 | P22310 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL307287 | 0.86 | CYP19A1 (0.58) | CYP19A1HDAC1HDAC6STS | |
| SCHEMBL14647083 | 0.81 | CYP19A1 (0.67) | CYP19A1HDAC1HDAC6STS | |
| SCHEMBL12268248 | 0.80 | CYP19A1 (0.44) | CYP19A1HDAC1HDAC6STS | |
| SCHEMBL305324 | 0.79 | CYP19A1 (0.73) | CYP19A1STS | |
| SCHEMBL10172779 | 0.77 | CYP19A1 (0.50) | CYP19A1HDAC1HDAC6STS | |
| SCHEMBL307543 | 0.75 | CYP19A1 (0.60) | CYP19A1HDAC1HDAC6STSUGT1A4 | |
| SCHEMBL3456043 | 0.75 | CYP19A1 (0.68) | CYP19A1HDAC1HDAC6UGT1A4PDE4D | |
| SCHEMBL3115446 | 0.73 | CYP19A1 (0.65) | CYP19A1HDAC1HDAC6STSUGT1A4 | |
| Hydrochloric Acid SCHEMBL11347612 | 0.72 | CYP19A1 (0.67) | CYP19A1HDAC1HDAC6STS | |
| SCHEMBL10066953 | 0.70 | CYP19A1 (0.65) | CYP19A1HDAC1HDAC6STSUGT1A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093279-B2 | Compound | STERIX LIMITED (GB) | 2012-01-10 | — | — | US | disclosed |
| US-20100173963-A1 | COMPOUND | STERIX LIMITED (GB) | 2010-07-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100173963-A1 | COMPOUND | CBR3, CBR1, OXSR1 | CYP19A1 605/4885HDAC1 1848/4885HDAC6 2791/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.