Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.34 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.32 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
| ▸ | BLM | P54132 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.32 |
| ▸ | HTR1A | P08908 | 1/20 | 0.32 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | HTR2B | P41595 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1011591 | 0.93 | EPHX1 (0.35) | HRH3EPHX1ALDH1A1TDP1ADRB2 | |
| SCHEMBL12759119 | 0.90 | HTR2A (0.33) | HRH3EPHX1ADRB2HTR1ASLC6A2 | |
| SCHEMBL12759132 | 0.88 | EPHX1 (0.34) | EPHX1ALDH1A1TDP1SLC6A2HTR2A | |
| SCHEMBL12759113 | 0.87 | SLC6A2 (0.36) | EPHX1ALDH1A1SLC6A2HTR2ASLC6A4 | |
| SCHEMBL12759125 | 0.87 | EPHX1 (0.33) | EPHX1ALDH1A1TDP1HTR2AHTR2B | |
| SCHEMBL1013572 | 0.87 | HTR2A (0.34) | HRH3ALDH1A1ADRB2HTR1ASLC6A2 | |
| SCHEMBL12760074 | 0.87 | HTR2A (0.34) | HRH3ALDH1A1ADRB2HTR1ASLC6A2 | |
| SCHEMBL12760234 | 0.87 | HTR2A (0.34) | HRH3ALDH1A1ADRB2HTR1ASLC6A2 | |
| SCHEMBL12759230 | 0.85 | HRH3 (0.34) | HRH3ALDH1A1TDP1ADRB2HTR1A | |
| SCHEMBL12759131 | 0.85 | SMN1; SMN2 (0.34) | ALDH1A1TDP1HTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2272837-B1 | LIQUID CRYSTALLINE COMPOUND WITH NEGATIVE DIELECTRIC ANISOTROPY, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | JNC CORP (JP) | 2014-12-17 | — | — | EP | disclosed |
| EP-2272837-A1 | LIQUID CRYSTALLINE COMPOUND WITH NEGATIVE DIELECTRIC ANISOTROPY, LIQUID CRYSTAL COMPOSITION, AND LIQUID CRYSTAL DISPLAY DEVICE | Chisso Corporation (JP) | 2011-01-12 | — | — | EP | disclosed |