⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1485518 | 1.00 | — | — | |
| SCHEMBL2623479 | 1.00 | — | — | |
| SCHEMBL265822 | 0.87 | TSHR (0.50) | — | |
| Alcohol SCHEMBL28286197 | 0.85 | TSHR (0.43) | — | |
| SCHEMBL26914655 | 0.82 | TSHR (0.46) | — | |
| SCHEMBL10604327 | 0.81 | TSHR (0.40) | — | |
| SCHEMBL13898781 | 0.81 | TSHR (0.40) | — | |
| SCHEMBL122160 | 0.81 | TSHR (0.40) | — | |
| SCHEMBL7886893 | 0.80 | — | — | |
| SCHEMBL9292915 | 0.80 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE49556-E1 | Compounds and compositions as protein kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2023-06-20 | — | — | US | disclosed |
| EP-3661901-A1 | SYNTHESIS OF GLYCOLS VIA TRANSFER HYDROGENATION OF ALPHA-FUNCTIONAL ESTERS WITH ALCOHOLS | Eastman Chemical Company (US) | 2020-06-10 | — | — | EP | disclosed |
| WO-2019027948-A1 | SYNTHESIS OF GLYCOLS VIA TRANSFER HYDROGENATION OF ALPHA-FUNCTIONAL ESTERS WITH ALCOHOLS | EASTMAN CHEMICAL COMPANY (US) | 2019-02-07 | — | — | WO | disclosed |
| US-10005761-B2 | Compounds and compositions as protein kinase inhibitors | ARRAY BIOPHARMA INC. (US) | 2018-06-26 | — | — | US | disclosed |
| US-9850230-B2 | Compounds and compositions as protein kinase inhibitors | ARRAY BIOPHARMA, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-9850229-B2 | Compounds and compositions as protein kinase inhibitors | ARRAY BIOPHARMA, INC. (US) | 2017-12-26 | — | — | US | disclosed |
| US-9593100-B2 | Compounds and compositions as protein kinase inhibitors | ARRAY BIOPHARMA, INC. (US) | 2017-03-14 | — | — | US | disclosed |
| US-9593099-B2 | Compounds and compositions as protein kinase inhibitors | ARRAY BIOPHARMA, INC. (US) | 2017-03-14 | — | — | US | disclosed |
| US-20160280686-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | IRM LLC (BM) | 2016-09-29 | — | — | US | disclosed |
| US-20160280687-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | NOVARTIS INTERNATIONAL PHARMACEUTICAL LTD. (BM) | 2016-09-29 | — | — | US | disclosed |
| CN-102884053-B | Cyclopropanecarboxylic acid derivatives | DAIICHI SANKYO Co.,Ltd. (JP) | 2016-03-02 | — | — | CN | disclosed |
| US-9248140-B2 | Chemical compounds | ASTRAZENECA AB (SE) | 2016-02-02 | — | — | US | disclosed |
| US-20150328239-A1 | Chemical Compounds | ASTRAZENECA AB (SE) | 2015-11-19 | — | — | US | disclosed |
| US-9018381-B2 | Chemical compounds | ASTRAZENECA AB (SE) | 2015-04-28 | — | — | US | disclosed |
| US-20130310344-A1 | N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS | ASTRAZENECA AB (UK) | 2013-11-21 | — | — | US | disclosed |
| US-20130296318-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | ARRAY BIOPHARMA, INC. | 2013-11-07 | — | — | US | disclosed |
| US-8501758-B2 | Compounds and compositions as protein kinase inhibitors | IRM LLC (BM) | 2013-08-06 | — | — | US | disclosed |
| CN-102884053-A | Cyclopropanecarboxylic acid derivatives | DAIICHI SANKYO CO LTD | 2013-01-16 | — | — | CN | disclosed |
| US-20120035134-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2012-02-09 | — | — | US | disclosed |
| US-20110306625-A1 | COMPOUNDS AND COMPOSITIONS AS PROTEIN KINASE INHIBITORS | NOVARTIS AG (CH) | 2011-12-15 | — | — | US | disclosed |