Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 4/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.40 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.40 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.40 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.38 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.38 |
| ▸ | ESR1 | P03372 | 1/20 | 0.36 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.36 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29163065 | 0.82 | ESR1 (0.56) | MEN1KMT2AESR1ESR2SLC6A4 | |
| SCHEMBL31239238 | 0.82 | ESR1 (0.56) | MEN1KMT2AESR1ESR2SLC6A4 | |
| SCHEMBL10178596 | 0.82 | ESR1 (0.36) | MEN1KMT2AESR1ESR2SLC6A4 | |
| SCHEMBL12054100 | 0.81 | ESR1 (0.46) | MEN1KMT2ANPSR1CYP19A1ESR1 | |
| SCHEMBL13930871 | 0.80 | MEN1 (0.52) | MEN1KMT2ANPSR1CYP19A1ESR1 | |
| SCHEMBL10179398 | 0.79 | MEN1 (0.48) | MEN1KMT2AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL20927022 | 0.78 | SMN1; SMN2 (0.44) | MEN1KMT2ANPSR1CYP19A1ESR1 | |
| SCHEMBL25946132 | 0.76 | KMT2A (0.55) | MEN1KMT2AGRIN2DGRIN3BGRIN1 | |
| SCHEMBL19286941 | 0.75 | ESR1 (0.40) | MEN1KMT2AESR1ESR2CYP3A4 | |
| SCHEMBL21216519 | 0.75 | MEN1 (0.48) | MEN1KMT2AGRIN2DGRIN3BGRIN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012012477-A1 | SUBSTITUTED 3-PHENYL-1,2,4-OXADIAZOLE COMPOUNDS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-01-26 | — | — | WO | disclosed |