Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 15/20 | 0.79 |
| ▸ | PLG | P00747 | 1/20 | 0.60 |
| ▸ | PLAT | P00750 | 1/20 | 0.60 |
| ▸ | KLK1 | P06870 | 1/20 | 0.60 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.53 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | F2 | P00734 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10181480 | 0.90 | F10 (0.77) | F10PLGPLATKLK1PRSS1 | |
| SCHEMBL13348900 | 0.90 | F10 (0.64) | F10PLGPLATKLK1PRSS1 | |
| SCHEMBL10178330 | 0.89 | F10 (0.75) | F10PLGPLATKLK1PRSS1 | |
| SCHEMBL14310049 | 0.88 | F10 (0.66) | F10PLGPLATKLK1PRSS1 | |
| SCHEMBL890901 | 0.88 | F10 (1.00) | F10PLGPLATKLK1PRSS1 | |
| SCHEMBL10178095 | 0.87 | F10 (0.61) | F10PLGPLATKLK1PRSS1 | |
| SCHEMBL10179032 | 0.83 | F10 (0.77) | F10PLGPLATKLK1PRSS1 | |
| SCHEMBL10178363 | 0.78 | F10 (0.53) | F10PLGPLATKLK1PRSS1 | |
| SCHEMBL890654 | 0.77 | F10 (1.00) | F10PLGPLATKLK1PRSS1 | |
| SCHEMBL7439982 | 0.77 | F10 (0.86) | F10PLGPLATKLK1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120083602-A1 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA | MILLENNIUM PHARMACEUTICALS, INC. | 2012-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120083602-A1 | BENZAMIDES AND RELATED INHIBITORS OF FACTOR XA | TFPI, F12, TFPI2 | F10 13/4885PLG 18/4885PLAT 25/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.