Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 20/20 | 0.70 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12827079 | 1.00 | CCNT1 (0.70) | CCNT1 | |
| SCHEMBL1463033 | 0.89 | CCNT1 (0.68) | CCNT1 | |
| SCHEMBL1946520 | 0.87 | CCNT1 (0.55) | CCNT1 | |
| SCHEMBL1192607 | 0.83 | CCNT1 (0.54) | CCNT1 | |
| SCHEMBL12889668 | 0.83 | CCNT1 (1.00) | CCNT1 | |
| SCHEMBL12889467 | 0.83 | CCNT1 (1.00) | CCNT1 | |
| SCHEMBL1462699 | 0.82 | CCNT1 (0.55) | CCNT1 | |
| SCHEMBL12889593 | 0.82 | CCNT1 (1.00) | CCNT1 | |
| SCHEMBL1463721 | 0.82 | CCNT1 (0.55) | CCNT1 | |
| SCHEMBL1947398 | 0.82 | CCNT1 (0.55) | CCNT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012101063-A1 | N-ACYL PYRIDINE BIARYL COMPOUNDS AND THEIR USES | NOVARTIS AG (CH) | 2012-08-02 | — | — | WO | disclosed |
| WO-2012101064-A1 | N-ACYL PYRIMIDINE BIARYL COMPOUNDS AS PROTEIN KINASE INHIBITORS | NOVARTIS AG (CH) | 2012-08-02 | — | — | WO | disclosed |
| WO-2012101062-A1 | SUBSTITUTED BI-HETEROARYL COMPOUNDS AS CDK9 INHIBITORS AND THEIR USES | NOVARTIS AG (CH) | 2012-08-02 | — | — | WO | disclosed |
| EP-2473499-A1 | BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | Novartis AG (CH) | 2012-07-11 | — | — | EP | disclosed |
| WO-2011026911-A1 | BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | NOVARTIS AG (CH) | 2011-03-10 | — | — | WO | disclosed |