SCHEMBL10179422

SCHEMBL10179422

Nc1cc(-c2cccc(NCc3cc(F)cc(F)c3)n2)c(Cl)cn1

nearest known ligand 0.85

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCNT1 O60563 20/20 0.85

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1462626 0.92 CCNT1 (1.00) CCNT1
SCHEMBL12850433 0.85 CCNT1 (0.72) CCNT1
SCHEMBL12889530 0.82 CCNT1 (0.82) CCNT1
SCHEMBL12889742 0.81 CCNT1 (0.77) CCNT1
SCHEMBL1192223 0.81 CCNT1 (0.80) CCNT1
SCHEMBL30859468 0.81 CCNT1 (0.80) CCNT1
SCHEMBL1192051 0.80 CCNT1 (1.00) CCNT1
SCHEMBL12898599 0.79 CCNT1 (0.88) CCNT1
SCHEMBL12898174 0.79 CCNT1 (0.78) CCNT1
SCHEMBL12889594 0.79 CCNT1 (0.85) CCNT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2473499-A1 BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES Novartis AG (CH) 2012-07-11 EP disclosed