SCHEMBL10179634

SCHEMBL10179634

CC1(C)COC[C@H](CNc2cccc(-c3cc(N)ncc3Cl)n2)O1

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CCNT1 O60563 20/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1462895 1.00 CCNT1 (0.53) CCNT1
SCHEMBL10180457 1.00 CCNT1 (0.53) CCNT1
SCHEMBL1463095 0.89 CCNT1 (0.52) CCNT1
SCHEMBL12827087 0.86 CCNT1 (0.52) CCNT1
SCHEMBL1462580 0.86 CCNT1 (0.54) CCNT1
SCHEMBL12849898 0.85 CCNT1 (0.63) CCNT1
SCHEMBL1463752 0.84 CCNT1 (0.47) CCNT1
SCHEMBL10179251 0.84 CCNT1 (0.47) CCNT1
SCHEMBL1192840 0.79 CCNT1 (0.64) CCNT1
SCHEMBL1462699 0.79 CCNT1 (0.55) CCNT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2473499-A1 BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES Novartis AG (CH) 2012-07-11 EP disclosed