Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 19/20 | 0.61 |
| ▸ | CDK9 | P50750 | 4/20 | 0.55 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.47 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.47 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12501767 | 0.88 | CCNT1 (0.59) | CCNT1 | |
| SCHEMBL10179002 | 0.85 | CCNT1 (0.58) | CCNT1CDK9 | |
| SCHEMBL10179196 | 0.83 | CCNT1 (0.60) | CCNT1CDK9 | |
| SCHEMBL12501658 | 0.83 | CCNT1 (0.48) | CCNT1CDK9 | |
| SCHEMBL1463033 | 0.81 | CCNT1 (0.68) | CCNT1CDK9HDAC3HDAC1HDAC6 | |
| SCHEMBL1192532 | 0.81 | CCNT1 (0.72) | CCNT1CDK9 | |
| SCHEMBL12827065 | 0.80 | CCNT1 (0.75) | CCNT1CDK9HDAC3HDAC1HDAC6 | |
| SCHEMBL12826904 | 0.78 | CCNT1 (0.69) | CCNT1CDK9HDAC3HDAC1HDAC6 | |
| SCHEMBL1946717 | 0.78 | CCNT1 (0.63) | CCNT1CDK9HDAC3HDAC1HDAC6 | |
| SCHEMBL10181535 | 0.78 | CCNT1 (0.44) | CCNT1CDK9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473499-A1 | BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | Novartis AG (CH) | 2012-07-11 | — | — | EP | claimed |
| EP-2473499-A1 | BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | Novartis AG (CH) | 2012-07-11 | — | — | EP | disclosed |