Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.75 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.70 |
| ▸ | FERMT2 | Q96AC1 | 4/20 | 0.68 |
| ▸ | CDK1 | P06493 | 1/20 | 0.66 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.66 |
| ▸ | BCHE | P06276 | 1/20 | 0.62 |
| ▸ | ACHE | P22303 | 1/20 | 0.62 |
| ▸ | HRH3 | Q9Y5N1 | 2/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.57 |
| ▸ | HTT | P42858 | 1/20 | 0.57 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.57 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13758769 | 0.93 | CCR1 (0.86) | CCR1CYP1A2FERMT2NR4A2BCHE | |
| SCHEMBL23640948 | 0.92 | CCR1 (0.89) | CCR1CYP1A2FERMT2NR4A2BCHE | |
| SCHEMBL18163919 | 0.92 | CCR1 (0.89) | CCR1CYP1A2FERMT2NR4A2BCHE | |
| SCHEMBL23640853 | 0.91 | CCR1 (0.81) | CCR1CYP1A2FERMT2NR4A2BCHE | |
| SCHEMBL19407562 | 0.91 | CCR1 (0.91) | CCR1CYP1A2FERMT2NR4A2HRH3 | |
| SCHEMBL17527102 | 0.89 | CCR1 (0.89) | CCR1CYP1A2FERMT2NR4A2HRH3 | |
| SCHEMBL2528053 | 0.89 | CCR1 (0.83) | CCR1CYP1A2FERMT2CDK1NR4A2 | |
| SCHEMBL19399300 | 0.89 | CCR1 (0.89) | CCR1CYP1A2FERMT2NR4A2HRH3 | |
| SCHEMBL1855080 | 0.89 | CYP1A2 (0.82) | CCR1CYP1A2FERMT2CDK1NR4A2 | |
| SCHEMBL11757988 | 0.88 | CCR1 (0.86) | CCR1CYP1A2FERMT2CDK1NR4A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2474528-B1 | Antineoplasic compounds and pharmaceutical compositions thereof | CT INGENIERIA GENETICA BIOTECH (CU) | 2014-09-24 | — | — | EP | claimed |
| EP-2474528-A1 | Antineoplasic compounds and pharmaceutical compositions thereof | Centro De Ingenieria Genetica Y Biotecnologia (CU) | 2012-07-11 | — | — | EP | claimed |