Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G1B | P04054 | 2/20 | 0.50 |
| ▸ | ATG4B | Q9Y4P1 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 4/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 3/20 | 0.46 |
| ▸ | MAOA | P21397 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.46 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL3112636 | 0.98 | PLA2G1B (0.49) | PLA2G1BATG4BTSHRLMNAKMT2A | |
| SCHEMBL10590731 | 0.80 | PLA2G1B (0.55) | PLA2G1BATG4BLMNAKMT2AMAOB | |
| SCHEMBL17777347 | 0.77 | PLA2G1B (0.52) | PLA2G1BATG4BTSHRLMNAKMT2A | |
| SCHEMBL5447702 | 0.76 | HPGD (0.47) | PLA2G1BATG4BTSHRLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL19371473 | 0.76 | PLA2G1B (0.50) | PLA2G1BATG4BTSHRLMNAKMT2A | |
| SCHEMBL4015337 | 0.76 | PLA2G1B (0.59) | PLA2G1BATG4BTSHRLMNAKMT2A | |
| SCHEMBL16216177 | 0.76 | PLA2G1B (0.59) | PLA2G1BATG4BLMNAKMT2AMAOB | |
| SCHEMBL13158620 | 0.76 | PLA2G1B (0.59) | PLA2G1BATG4BTSHRLMNAKMT2A | |
| Hydrochloric Acid SCHEMBL27636314 | 0.74 | PLA2G1B (0.57) | PLA2G1BATG4BTSHRLMNAKMT2A | |
| SCHEMBL19321442 | 0.73 | TSHR (0.59) | PLA2G1BATG4BTSHRLMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2474525-A2 | Ligands for imaging cardiac innervation | Lantheus Medical Imaging, Inc. (US) | 2012-07-11 | — | — | EP | disclosed |