Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 5/20 | 0.93 |
| ▸ | CNR1 | P21554 | 5/20 | 0.74 |
| ▸ | CNR2 | P34972 | 2/20 | 0.72 |
| ▸ | FAAH | O00519 | 3/20 | 0.71 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.71 |
| ▸ | MEN1 | O00255 | 2/20 | 0.71 |
| ▸ | MAPT | P10636 | 2/20 | 0.71 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.71 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 1/20 | 0.71 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.71 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.71 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.66 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10180474 | 1.00 | EPHX2 (0.93) | EPHX2CNR1CNR2FAAHALOX12 | |
| SCHEMBL28665630 | 0.96 | EPHX2 (1.00) | EPHX2CNR1CNR2FAAHALOX12 | |
| SCHEMBL22411430 | 0.94 | EPHX2 (0.95) | EPHX2CNR1CNR2FAAHALOX12 | |
| SCHEMBL6511518 | 0.89 | CNR1 (0.77) | EPHX2CNR1CNR2FAAHALOX12 | |
| SCHEMBL6511512 | 0.89 | CNR1 (0.77) | EPHX2CNR1CNR2FAAHALOX12 | |
| SCHEMBL18248591 | 0.87 | EPHX2 (1.00) | EPHX2CNR1CNR2FAAHMEN1 | |
| SCHEMBL7426779 | 0.86 | EPHX2 (0.78) | EPHX2HPGDTRPV1 | |
| SCHEMBL10066131 | 0.86 | EPHX2 (0.82) | EPHX2CNR1CNR2FAAHMAPT | |
| SCHEMBL1456740 | 0.85 | EPHX2 (0.80) | EPHX2MEN1MAPTKMT2AHPGD | |
| SCHEMBL19043177 | 0.85 | EPHX2 (0.80) | EPHX2MEN1MAPTKMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1636335-B1 | COMPOSITIONS AND METHODS FOR INHIBITING AN ISOFORM OF HUMAN MANGANESE SUPEROXIDE DISMUTASE | MITO TEK LLC (US) | 2012-07-11 | — | — | EP | claimed |