Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 18/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.39 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.39 |
| ▸ | MLNR | O43193 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10180492 | 1.00 | STAT3 (0.47) | STAT3SCN9ASCN10AMLNR | |
| SCHEMBL3060639 | 0.94 | STAT3 (0.41) | STAT3MLNR | |
| SCHEMBL3045913 | 0.92 | STAT3 (0.56) | STAT3 | |
| SCHEMBL3045917 | 0.92 | STAT3 (0.56) | STAT3 | |
| SCHEMBL10180672 | 0.91 | STAT3 (0.57) | STAT3 | |
| Bromide SCHEMBL3056336 | 0.90 | STAT3 (0.56) | STAT3 | |
| Bromide SCHEMBL3060740 | 0.88 | STAT3 (0.50) | STAT3 | |
| Bromide SCHEMBL10181522 | 0.88 | STAT3 (0.50) | STAT3 | |
| SCHEMBL15295444 | 0.86 | STAT3 (0.57) | STAT3 | |
| Bromide SCHEMBL3059647 | 0.85 | STAT3 (0.52) | STAT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207773-B1 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMA CO LTD (JP) | 2012-07-11 | — | — | EP | disclosed |