Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 16/20 | 0.53 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.51 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3065084 | 0.99 | STAT3 (0.53) | STAT3PIK3CAPRKAA2USP2HPGD | |
| SCHEMBL15295489 | 0.93 | STAT3 (0.52) | STAT3PIK3CAPRKAA2USP2HPGD | |
| Bromide SCHEMBL3066691 | 0.93 | STAT3 (0.52) | STAT3PIK3CAPRKAA2USP2HPGD | |
| Hydrochloric Acid SCHEMBL3061098 | 0.91 | STAT3 (0.50) | STAT3PIK3CAPRKAA2USP2HPGD | |
| Bromide SCHEMBL3067802 | 0.90 | STAT3 (0.51) | STAT3PIK3CAPRKAA2USP2HPGD | |
| Hydrochloric Acid SCHEMBL3062529 | 0.90 | STAT3 (0.49) | STAT3PIK3CAPRKAA2USP2HPGD | |
| SCHEMBL3706315 | 0.89 | STAT3 (0.55) | STAT3PIK3CAPRKAA2SCN9A | |
| Bromide SCHEMBL3050200 | 0.89 | STAT3 (0.47) | STAT3PIK3CAPRKAA2USP2HPGD | |
| SCHEMBL10180854 | 0.89 | MEN1 (0.49) | STAT3USP2HPGD | |
| Bromide SCHEMBL3052222 | 0.89 | STAT3 (0.49) | STAT3PIK3CAPRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207773-B1 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMA CO LTD (JP) | 2012-07-11 | — | — | EP | disclosed |