Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 13/20 | 0.49 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.47 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | LIPE | Q05469 | 1/20 | 0.42 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.41 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.41 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.41 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.41 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.41 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | TNF | P01375 | 1/20 | 0.41 |
| ▸ | NOD1 | Q9Y239 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Oxalic Acid SCHEMBL3051557 | 0.98 | STAT3 (0.47) | STAT3PRKAA2PIK3CAMAPTL3MBTL1 | |
| SCHEMBL3062237 | 0.90 | STAT3 (0.49) | STAT3PRKAA2PIK3CAMAPTL3MBTL1 | |
| SCHEMBL3062240 | 0.90 | MAPT (0.46) | STAT3PRKAA2PIK3CAMAPTL3MBTL1 | |
| SCHEMBL10181380 | 0.89 | STAT3 (0.48) | STAT3PRKAA2PIK3CAMAPTL3MBTL1 | |
| Oxalic Acid SCHEMBL3069686 | 0.88 | STAT3 (0.46) | STAT3PRKAA2PIK3CAMAPTHTT | |
| SCHEMBL3059426 | 0.88 | MAPT (0.55) | STAT3PRKAA2PIK3CAMAPTL3MBTL1 | |
| Oxalic Acid SCHEMBL3051563 | 0.88 | STAT3 (0.47) | STAT3PRKAA2PIK3CAMAPTL3MBTL1 | |
| SCHEMBL10180601 | 0.88 | STAT3 (0.62) | STAT3PRKAA2PIK3CAPRKAB2PRKAG1 | |
| Oxalic Acid SCHEMBL15295456 | 0.86 | STAT3 (0.60) | STAT3PRKAA2PIK3CAPRKAB2PRKAG1 | |
| SCHEMBL3051748 | 0.83 | SCN9A (0.53) | STAT3MAPTL3MBTL1GAAMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8551999-B2 | Heterocyclic compound and pharmaceutical composition thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-10-08 | — | — | US | claimed |
| EP-2207773-B1 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMA CO LTD (JP) | 2012-07-11 | — | — | EP | claimed |