Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 15/20 | 0.44 |
| ▸ | MLNR | O43193 | 1/20 | 0.43 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.43 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.43 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Fumaric Acid SCHEMBL3062043 | 0.96 | STAT3 (0.42) | STAT3MLNRPIK3CAPRKAA2 | |
| Maleic Acid SCHEMBL3062041 | 0.96 | STAT3 (0.42) | STAT3MLNRPIK3CAPRKAA2 | |
| Bromide SCHEMBL3046046 | 0.94 | STAT3 (0.49) | STAT3MLNR | |
| SCHEMBL3046815 | 0.92 | PIK3CA (0.44) | STAT3MLNRPIK3CAPRKAA2 | |
| Bromide SCHEMBL3061151 | 0.91 | STAT3 (0.45) | STAT3MLNRHRH3 | |
| Bromide SCHEMBL10181379 | 0.91 | PIK3CA (0.51) | STAT3MLNRPIK3CAPRKAA2HRH3 | |
| Bromide SCHEMBL3064130 | 0.91 | STAT3 (0.44) | STAT3MLNRPIK3CAPRKAA2HRH3 | |
| SCHEMBL10180586 | 0.90 | STAT3 (0.54) | STAT3PIK3CAPRKAA2 | |
| Maleic Acid SCHEMBL3069658 | 0.89 | STAT3 (0.45) | STAT3PIK3CAPRKAA2HRH3 | |
| Fumaric Acid SCHEMBL3069662 | 0.89 | STAT3 (0.45) | STAT3PIK3CAPRKAA2HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2207773-B1 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMA CO LTD (JP) | 2012-07-11 | — | — | EP | disclosed |