Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCNT1 | O60563 | 19/20 | 0.59 |
| ▸ | CDK9 | P50750 | 8/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | GAA | P10253 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1462808 | 1.00 | CCNT1 (0.59) | CCNT1CDK9KDM4EALDH1A1GAA | |
| SCHEMBL1191677 | 0.90 | CCNT1 (0.57) | CCNT1CDK9KDM4EALDH1A1GAA | |
| SCHEMBL12827091 | 0.87 | CCNT1 (0.54) | CCNT1CDK9KDM4EALDH1A1GAA | |
| SCHEMBL1192670 | 0.87 | CCNT1 (0.65) | CCNT1CDK9 | |
| SCHEMBL1461838 | 0.86 | CCNT1 (0.68) | CCNT1CDK9 | |
| SCHEMBL1462699 | 0.86 | CCNT1 (0.55) | CCNT1CDK9 | |
| SCHEMBL1947398 | 0.86 | CCNT1 (0.55) | CCNT1CDK9 | |
| SCHEMBL1463721 | 0.86 | CCNT1 (0.55) | CCNT1CDK9 | |
| SCHEMBL1192042 | 0.85 | CCNT1 (0.78) | CCNT1CDK9 | |
| SCHEMBL12811678 | 0.83 | KDM4E (0.53) | CCNT1CDK9KDM4EALDH1A1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2473499-A1 | BIPYRIDINES USEFUL FOR THE TREATMENT OF PROLIFERATIVE DISEASES | Novartis AG (CH) | 2012-07-11 | — | — | EP | disclosed |