Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR7 | Q9NYK1 | 6/20 | 0.35 |
| ▸ | LMNA | P02545 | 3/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | HRH2 | P25021 | 1/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.35 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | NUDT1 | P36639 | 1/20 | 0.35 |
| ▸ | HTR2B | P41595 | 1/20 | 0.35 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | CASP1 | P29466 | 2/20 | 0.35 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.35 |
| ▸ | TLR8 | Q9NR97 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4979244 | 0.87 | TLR7 (0.45) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL10180932 | 0.84 | TLR7 (0.34) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL3251879 | 0.84 | TLR7 (0.39) | TLR7PDE4DTLR8 | |
| SCHEMBL841902 | 0.80 | TLR7 (0.43) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL12245253 | 0.74 | TLR7 (0.40) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL12296518 | 0.74 | TLR7 (0.41) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL30448090 | 0.73 | TLR7 (0.39) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL143565 | 0.73 | TLR7 (0.39) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL31092876 | 0.72 | TLR7 (0.38) | TLR7LMNAPOLBHRH2ADRA1D | |
| SCHEMBL142891 | 0.72 | TLR7 (0.38) | TLR7LMNAPOLBHRH2ADRA1D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2019686-B1 | COMBINED MUCOSAL AND PARENTERAL IMMUNIZATION AGAINST HIV | NOVARTIS AG (CH) | 2012-07-11 | — | — | EP | disclosed |