Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 19/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.48 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL10180685 | 0.99 | STAT3 (0.51) | STAT3PIK3CAPRKAA2 | |
| SCHEMBL3059167 | 0.93 | STAT3 (0.49) | STAT3PIK3CAPRKAA2 | |
| Bromide SCHEMBL3051528 | 0.90 | STAT3 (0.53) | STAT3PIK3CAPRKAA2 | |
| SCHEMBL10180482 | 0.89 | STAT3 (0.55) | STAT3PIK3CAPRKAA2 | |
| Fumaric Acid SCHEMBL3061331 | 0.86 | PIK3CA (0.41) | STAT3PIK3CAPRKAA2 | |
| Maleic Acid SCHEMBL3061327 | 0.86 | PIK3CA (0.41) | STAT3PIK3CAPRKAA2 | |
| Maleic Acid SCHEMBL3063405 | 0.86 | STAT3 (0.52) | STAT3PIK3CAPRKAA2 | |
| Fumaric Acid SCHEMBL3063410 | 0.86 | STAT3 (0.52) | STAT3PIK3CAPRKAA2 | |
| SCHEMBL3062544 | 0.85 | SCN9A (0.45) | STAT3 | |
| Bromide SCHEMBL3056975 | 0.85 | STAT3 (0.57) | STAT3PIK3CAPRKAA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8551999-B2 | Heterocyclic compound and pharmaceutical composition thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-10-08 | — | — | US | claimed |
| EP-2207773-B1 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMA CO LTD (JP) | 2012-07-11 | — | — | EP | claimed |