Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | STAT3 | P40763 | 17/20 | 0.59 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.56 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.56 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.48 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.48 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.48 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.48 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL3056975 | 0.97 | STAT3 (0.57) | STAT3PRKAA2PIK3CA | |
| Maleic Acid SCHEMBL3056841 | 0.96 | STAT3 (0.56) | STAT3PRKAA2PIK3CAPRKAB2PRKAG1 | |
| Fumaric Acid SCHEMBL3056843 | 0.96 | STAT3 (0.56) | STAT3PRKAA2PIK3CAPRKAB2PRKAG1 | |
| SCHEMBL10181513 | 0.95 | STAT3 (0.55) | STAT3PRKAA2PIK3CA | |
| Bromide SCHEMBL3060644 | 0.94 | STAT3 (0.66) | STAT3PRKAA2PIK3CA | |
| SCHEMBL15295440 | 0.94 | STAT3 (0.60) | STAT3PRKAA2PIK3CA | |
| Bromide SCHEMBL3063793 | 0.94 | STAT3 (0.59) | STAT3PRKAA2PIK3CA | |
| SCHEMBL10180482 | 0.94 | STAT3 (0.55) | STAT3PRKAA2PIK3CA | |
| Bromide SCHEMBL3056616 | 0.94 | STAT3 (0.52) | STAT3PRKAA2PIK3CA | |
| Bromide SCHEMBL3067475 | 0.93 | STAT3 (0.59) | STAT3PRKAA2PIK3CA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8551999-B2 | Heterocyclic compound and pharmaceutical composition thereof | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 2013-10-08 | — | — | US | claimed |
| EP-2207773-B1 | HETEROCYCLIC COMPOUND AND PHARMACEUTICAL COMPOSITION THEREOF | OTSUKA PHARMA CO LTD (JP) | 2012-07-11 | — | — | EP | claimed |