Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | GAA | P10253 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.39 |
| ▸ | GAPDH | P04406 | 1/20 | 0.38 |
| ▸ | LGALS9 | O00182 | 1/20 | 0.37 |
| ▸ | LGALS1 | P09382 | 1/20 | 0.37 |
| ▸ | LGALS3 | P17931 | 1/20 | 0.37 |
| ▸ | LGALS7; LGALS7B | P47929 | 1/20 | 0.37 |
| ▸ | ABCB1 | P08183 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7746169 | 0.85 | MAPT (0.53) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL308252 | 0.85 | MAPT (0.53) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL27514476 | 0.85 | MAPT (0.53) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL11075412 | 0.85 | MAPT (0.53) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL308251 | 0.85 | MAPT (0.53) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL19460953 | 0.83 | MAPT (0.52) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL19460954 | 0.83 | MAPT (0.52) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL4960765 | 0.83 | MAPT (0.52) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL652994 | 0.83 | MAPT (0.52) | MAPTPOLBMEN1USP2KMT2A | |
| SCHEMBL4962623 | 0.83 | MAPT (0.52) | MAPTPOLBMEN1USP2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012093091-A2 | NEW SACCHARIDE MIMICS AND THEIR USE AS INHIBITORS OF ANGIOGENESIS AND METASTASIS FORMATION | DEUTSCHES KREBSFORSCHUNGSZENTRUM (DE) | 2012-07-12 | — | — | WO | disclosed |
| EP-2474552-A1 | New saccharide mimics and their use as inhibitors of angiogenesis and metastasis formation | Deutsches Krebsforschungszentrum (DE) | 2012-07-11 | — | — | EP | disclosed |