Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIK3C3 | Q8NEB9 | 3/20 | 0.33 |
| ▸ | ABL1 | P00519 | 1/20 | 0.31 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL626595 | 0.72 | PIK3C3 (0.42) | PIK3C3ABL1PTK2 | |
| SCHEMBL626666 | 0.70 | KDM4E (0.39) | PIK3C3ABL1PTK2 | |
| SCHEMBL626417 | 0.68 | PIK3C3 (0.39) | PIK3C3ABL1PTK2 | |
| SCHEMBL626235 | 0.67 | ABL1 (0.37) | PIK3C3ABL1PTK2 | |
| SCHEMBL627354 | 0.65 | PIK3C3 (0.43) | PIK3C3ABL1PTK2 | |
| SCHEMBL10182598 | 0.64 | PIK3C3 (0.38) | PIK3C3ABL1PTK2 | |
| SCHEMBL626945 | 0.64 | PIK3C3 (0.45) | PIK3C3ABL1PTK2 | |
| SCHEMBL626066 | 0.64 | PIK3C3 (0.45) | PIK3C3ABL1PTK2 | |
| SCHEMBL9109069 | 0.64 | PIK3C3 (0.41) | PIK3C3ABL1PTK2 | |
| SCHEMBL627473 | 0.64 | PIK3C3 (0.39) | PIK3C3ABL1PTK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012021615-A1 | HETEROARYLS AND USES THEREOF | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2012-02-16 | — | — | WO | disclosed |