SCHEMBL1018324

SCHEMBL1018324

C=COC(=O)c1cccc(Cl)c1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PARP1 P09874 1/20 0.52
ALDH1A1 P00352 3/20 0.48
KDM4E B2RXH2 2/20 0.48
USP2 O75604 1/20 0.48
ALOX15 P16050 1/20 0.48
NPSR1 Q6W5P4 1/20 0.48
GAA P10253 2/20 0.47
KMT2A Q03164 1/20 0.47
TDP1 Q9NUW8 1/20 0.46
MAPT P10636 1/20 0.45
HPGD P15428 1/20 0.45
HTT P42858 1/20 0.45
RAB9A P51151 2/20 0.44
L3MBTL1 Q9Y468 1/20 0.44
CHRM2 P08172 1/20 0.44
CHRM4 P08173 1/20 0.44
CHRM1 P11229 1/20 0.44
CHRM3 P20309 1/20 0.44
ERCC5 P28715 1/20 0.44
FEN1 P39748 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acetic Acid SCHEMBL27803028 0.94 PARP1 (0.46) PARP1ALDH1A1KDM4EUSP2ALOX15
SCHEMBL156225 0.87 ATM (0.41) ALDH1A1TDP1RAB9AL3MBTL1TSHR
SCHEMBL22734773 0.84 PARP1 (0.53) PARP1ALDH1A1KDM4EUSP2ALOX15
SCHEMBL31159599 0.83 PARP1 (0.46) PARP1ALDH1A1KDM4EUSP2ALOX15
SCHEMBL3062001 0.81 TPMT (0.46) ALDH1A1ALOX15GAAKMT2AMAPT
SCHEMBL4189018 0.80 CA12 (0.52) PARP1ALDH1A1KDM4ERAB9ANPC1
SCHEMBL9695513 0.80 UNG (0.47) KDM4ETDP1HPGDL3MBTL1TSHR
SCHEMBL6959263 0.79 PARP1 (0.57) PARP1ALDH1A1KDM4EUSP2ALOX15
SCHEMBL27803029 0.79 NPC1 (0.47) PARP1ALDH1A1GAAKMT2AMAPT
SCHEMBL2381176 0.79 PARP1 (0.61) PARP1ALDH1A1KDM4EUSP2ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 135 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180030237-A1 Environmentally Friendly Colorant Compositions and Latex Paints/Coatings COLUMBIA INSURANCE CO (US) 2018-02-01 US claimed
US-9815961-B2 Environmentally friendly colorant compositions and latex paints/coatings COLUMBIA INSURANCE COMPANY (US) 2017-11-14 US claimed
EP-1569977-B1 CURABLE COMPOSITIONS SHERWIN WILLIAMS CO (US) 2008-06-11 EP claimed
US-6271328-B1 FREE RADICAL ROUTE FOR OPTICAL ARTICLE FOR REFRACTIVE INDEX, ALLYL CARBONATES ENICHEM SYNTHESIS S.P.A., (IT) 2001-08-07 US claimed
EP-0331260-B1 Liquid, polymerisable composition yielding optical articles showing a high refractive index GREAT LAKES CHEMICAL ITALIA (IT) 1995-05-17 EP claimed
EP-0331260-A2 Liquid, polymerisable composition yielding optical articles showing a high refractive index GREAT LAKES CHEMICAL ITALIA S.r.l. (IT) 1989-09-06 EP claimed
US-20250270407-A1 MULTI-COMPONENT DIRECT TO METAL AND PLASTIC PRIMER SYSTEM SWIMC LLC 2025-08-28 US disclosed
WO-2025125375-A1 CATALYST COMPOSITION AND COATING COMPOSITIONS COMPRISING THE SAME BORCHERS GMBH (DE) 2025-06-19 WO disclosed
EP-2496615-B1 ENVIRONMENTALLY FRIENDLY COLORANT COMPOSITIONS AND LATEX PAINTS/COATINGS MOORE BENJAMIN & CO (US) 2019-09-18 EP disclosed
EP-1910458-B1 LATEX PAINT FILM RESISTANT TO ADVERSE EFFECTS OF WATER, AND COMPOSITIONS AND METHODS FOR MAKING SAME BENJAMIN MOORE&CO (US) 2018-02-21 EP disclosed
US-20180030237-A1 Environmentally Friendly Colorant Compositions and Latex Paints/Coatings COLUMBIA INSURANCE CO (US) 2018-02-01 US disclosed
US-9815961-B2 Environmentally friendly colorant compositions and latex paints/coatings COLUMBIA INSURANCE COMPANY (US) 2017-11-14 US disclosed
CN-102695730-B Environmentally friendly colorant compositions and latex paints/coatings COLUMBIA INSURANCE CO. (US) 2016-01-13 CN disclosed
US-4191674-A QUATERNARY AMMONIUM GROUP, DERIVED FROM AN EPOXY GROUP CONTAINING POLYMER PPG INDUSTRIES, INC. (US) 1980-03-04 US disclosed
US-4066592-A ZWITTERION-CONTAINING COMPOSITIONS PPG INDUSTRIES, INC. (US) 1978-01-03 US disclosed
US-4046577-A PHOTOREACTIVE COMPOSITIONS COMPRISING POLYMERS CONTAINING ALKOXYAROMATIC GLYOXY GROUPS THE RICHARDSON COMPANY (US) 1977-09-06 US disclosed
US-4031290-A ALPHA-BETA MONOMERS, CATALYSIS PPG INDUSTRIES, INC. (US) 1977-06-21 US disclosed
US-4016332-A OF ETHYLENICALLY UNSATURATED MONOMERS PPG INDUSTRIES, INC. (US) 1977-04-05 US disclosed
US-3939051-A Process for electrodeposition of cationic thermosetting compositions PPG INDUSTRIES, INC. (US) 1976-02-17 US disclosed
US-3933940-A Mercaptan blocked thermosetting copolymers PPG INDUSTRIES, INC. (US) 1976-01-20 US disclosed