SCHEMBL1018708

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1019583	0.94	HSP90AA1 (0.57)	HSP90AB1HSP90AA1HSP90B1ROCK1SLC6A9
	SCHEMBL13649863	0.93	HSP90AB1 (0.55)	HSP90AB1HSP90AA1HSP90B1ROCK1SLC6A9
	SCHEMBL1019796	0.90	HSP90AB1 (0.65)	HSP90AB1HSP90AA1HSP90B1ROCK1SLC6A9
	Hydrochloric Acid SCHEMBL1638060	0.89	HSP90AB1 (0.64)	HSP90AB1HSP90AA1HSP90B1ROCK1SLC6A9
	SCHEMBL1019460	0.88	HSP90AB1 (0.68)	HSP90AB1HSP90AA1HSP90B1ROCK1SLC6A9
	SCHEMBL1018434	0.88	HSP90AB1 (0.67)	HSP90AB1HSP90AA1HSP90B1ROCK1ROCK2
	SCHEMBL1017906	0.86	HSP90AA1 (0.65)	HSP90AB1HSP90AA1HSP90B1ROCK1ROCK2
	SCHEMBL1019641	0.86	HSP90AB1 (0.65)	HSP90AB1HSP90AA1HSP90B1ROCK1ROCK2
	SCHEMBL1020564	0.85	HSP90AA1 (0.71)	HSP90AB1HSP90AA1HSP90B1ROCK1ALK
	SCHEMBL1019008	0.84	HSP90AB1 (0.63)	HSP90AB1HSP90AA1HSP90B1ROCK1ROCK2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 21 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.