Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | ACACB | O00763 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MAOB | P27338 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
| ▸ | CASP1 | P29466 | 1/20 | 0.40 |
| ▸ | CASP7 | P55210 | 1/20 | 0.40 |
| ▸ | ATM | Q13315 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9072621 | 0.93 | TSHR (0.45) | MAPTKMT2AMAOBMEN1CA12 | |
| SCHEMBL11790185 | 0.87 | MAPT (0.51) | MAPTACACBKMT2AMAOBMEN1 | |
| SCHEMBL11796509 | 0.86 | MEN1 (0.54) | MAPTKMT2AMAOBMEN1KDM4E | |
| SCHEMBL13876611 | 0.85 | MAOB (0.40) | MAOBKDM4EUSP2ALDH1A1CASP1 | |
| SCHEMBL13482321 | 0.84 | MAOB (0.56) | MAPTACACBKMT2AMAOBCA12 | |
| SCHEMBL28017761 | 0.83 | MAOB (0.41) | MAPTKMT2AMAOBMEN1KDM4E | |
| SCHEMBL28017766 | 0.83 | MAOB (0.41) | MAPTKMT2AMAOBMEN1NPC1 | |
| SCHEMBL7356604 | 0.81 | PTGS1 (0.45) | MAPTACACBKMT2AMAOBCA12 | |
| SCHEMBL175022 | 0.80 | ACACB (0.42) | MAPTACACBKMT2AMAOBCA12 | |
| SCHEMBL1697625 | 0.80 | MAOB (0.45) | MAPTACACBKMT2AMAOBCA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |