Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DYRK1A | Q13627 | 2/20 | 0.49 |
| ▸ | KDM1A | O60341 | 1/20 | 0.43 |
| ▸ | SMPD3 | Q9NY59 | 1/20 | 0.40 |
| ▸ | ACACB | O00763 | 3/20 | 0.39 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.39 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.39 |
| ▸ | OGA | O60502 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.35 |
| ▸ | HCRTR2 | O43614 | 8/20 | 0.34 |
| ▸ | HCRTR1 | O43613 | 7/20 | 0.34 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.34 |
| ▸ | CDC7 | O00311 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30075754 | 0.84 | KDM1A (0.41) | DYRK1AKDM1AMKNK1MKNK2OGA | |
| SCHEMBL24969806 | 0.84 | KDM1A (0.41) | DYRK1AKDM1AMKNK1MKNK2OGA | |
| SCHEMBL23579347 | 0.82 | KDM1A (0.40) | DYRK1AKDM1AMKNK1MKNK2OGA | |
| SCHEMBL23593411 | 0.82 | KDM1A (0.40) | DYRK1AKDM1AMKNK1MKNK2OGA | |
| SCHEMBL30556681 | 0.80 | HCRTR2 (0.49) | DYRK1AACACBHCRTR2HCRTR1 | |
| SCHEMBL23593409 | 0.80 | KDM1A (0.46) | DYRK1AKDM1ASMPD3MKNK1MKNK2 | |
| SCHEMBL29959199 | 0.79 | KDM1A (0.42) | DYRK1AKDM1AMKNK1MKNK2OGA | |
| SCHEMBL23579408 | 0.79 | KDM1A (0.42) | DYRK1AKDM1AMKNK1MKNK2OGA | |
| SCHEMBL4949146 | 0.79 | MTOR (0.45) | KDM1AACACBMKNK1MKNK2OGA | |
| SCHEMBL10187275 | 0.77 | KDM1A (0.48) | DYRK1AKDM1AMKNK1MKNK2OGA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |