SCHEMBL10187570

SCHEMBL10187570

Cc1cc(OCc2ccccc2)cc(C)c1C1=C(O)[C@@H]2[C@H](C1=O)[C@H]1C=C[C@@H]2CC1

nearest known ligand 0.43

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
FFAR1 O14842 7/20 0.43
MAOB P27338 4/20 0.39
S1PR1 P21453 1/20 0.39
S1PR5 Q9H228 1/20 0.39
SRD5A1 P18405 1/20 0.38
MEN1 O00255 1/20 0.38
KMT2A Q03164 1/20 0.38
MAPT P10636 1/20 0.38
BRD4 O60885 1/20 0.37
MAOA P21397 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16281728 1.00 FFAR1 (0.43) FFAR1MAOBS1PR1S1PR5SRD5A1
SCHEMBL10187560 0.94 FFAR1 (0.43) FFAR1MAOBS1PR1S1PR5MEN1
SCHEMBL10187572 0.87 FFAR1 (0.42) FFAR1MAOBS1PR1S1PR5MEN1
SCHEMBL10187547 0.83 FFAR1 (0.41) FFAR1MAOBS1PR1S1PR5MEN1
SCHEMBL13262087 0.83 FFAR1 (0.41) FFAR1MAOBS1PR1S1PR5MEN1
SCHEMBL515347 0.76 SRD5A1 (0.41) MAOBS1PR1S1PR5SRD5A1MEN1
SCHEMBL10192897 0.72 BRD4 (0.51) FFAR1MAOBMEN1KMT2ABRD4
SCHEMBL13261915 0.72 FFAR1 (0.39) FFAR1MAOBS1PR1S1PR5MEN1
SCHEMBL515151 0.72 FFAR1 (0.41) FFAR1MAOBS1PR1S1PR5MEN1
SCHEMBL516169 0.69 MAOB (0.41) MAOBS1PR1S1PR5SRD5A1MEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8680339-B2 Herbicides SYNGENTA LIMITED (GB) 2014-03-25 US disclosed
US-8680339-B2 Herbicides SYNGENTA LIMITED (GB) 2014-03-25 US disclosed
US-20120028800-A1 NOVEL HERBICIDES SYNGENTA CROP PROTECTION LLC (US) 2012-02-02 US disclosed
US-20120028800-A1 NOVEL HERBICIDES SYNGENTA CROP PROTECTION LLC (US) 2012-02-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120028800-A1 NOVEL HERBICIDES DDT, CYP4X1, CYP1B1 FFAR1 752/4885MAOB 2064/4885S1PR1 3494/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.