Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 13/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | HTR1A | P08908 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | HTR2A | P28223 | 1/20 | 0.40 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9932038 | 0.85 | ACACB (0.76) | ACACB | |
| SCHEMBL9932036 | 0.85 | ACACB (0.76) | ACACB | |
| SCHEMBL9966757 | 0.72 | ACACB (0.70) | ACACB | |
| SCHEMBL17207059 | 0.71 | ACACB (1.00) | ACACB | |
| SCHEMBL15849128 | 0.70 | ACACB (0.78) | ACACB | |
| SCHEMBL14990649 | 0.70 | ACACB (0.63) | ACACB | |
| SCHEMBL17366318 | 0.69 | ACACB (0.59) | ACACBHTR2A | |
| SCHEMBL15048248 | 0.68 | ACACB (1.00) | ACACB | |
| SCHEMBL469040 | 0.67 | HTR2C (0.58) | MAPT | |
| SCHEMBL15053270 | 0.66 | ACACB (0.81) | ACACB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012001107-A1 | PIPERIDINE DERIVATIVES AND THEIR USE FOR THE TREATMENT OF METABOLIC DISORDERS | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2012-01-05 | — | — | WO | disclosed |