SCHEMBL1018903

SCHEMBL1018903

CCOP(=O)(CC)OCCO

nearest known ligand 0.68

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.68
PPARD Q03181 2/20 0.58
ALDH1A1 P00352 1/20 0.39
TP53 P04637 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
CA12 O43570 1/20 0.35
CA1 P00915 1/20 0.35
CA2 P00918 1/20 0.35
CA9 Q16790 1/20 0.35
ACHE P22303 1/20 0.33
MEN1 O00255 1/20 0.31
GAA P10253 1/20 0.31
CYP2C9 P11712 1/20 0.31
CYP2C19 P33261 1/20 0.31
KMT2A Q03164 1/20 0.31
LPAR1 Q92633 2/20 0.30
LPAR3 Q9UBY5 2/20 0.30
LPAR2 Q9HBW0 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10442078 0.84 TSHR (0.58) TSHRPPARDALDH1A1TP53TDP1
SCHEMBL27827115 0.83 TSHR (0.44) TSHRPPARDALDH1A1
SCHEMBL5961215 0.83 TSHR (1.00) TSHRPPARDTP53TDP1ACHE
SCHEMBL26483 0.83 TSHR (1.00) TSHRPPARDTP53TDP1ACHE
SCHEMBL3361435 0.81 TSHR (0.75) TSHRPPARDTP53TDP1CA12
SCHEMBL585292 0.81 TSHR (0.75) TSHRPPARDTP53TDP1CA12
SCHEMBL2405777 0.81 PPARD (0.63) TSHRPPARDALDH1A1TP53TDP1
SCHEMBL3196771 0.81 TSHR (0.54) TSHRPPARDTP53TDP1CA12
SCHEMBL11647832 0.80 MEN1 (0.48) TSHRPPARDALDH1A1MEN1KMT2A
SCHEMBL11745101 0.80 TSHR (0.94) TSHRPPARDTP53TDP1ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 25 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-114634700-B Aerogel modified polyurethane foam heat insulation board and preparation method thereof 重庆再升科技股份有限公司 2023-10-24 CN claimed
CN-116517129-A Modified polyurethane foam heat insulation board and preparation method thereof 唐宽 2023-08-01 CN claimed
CN-114634700-B Aerogel modified polyurethane foam heat insulation board and preparation method thereof 重庆再升科技股份有限公司 2023-10-24 CN disclosed
CN-116517129-A Modified polyurethane foam heat insulation board and preparation method thereof 唐宽 2023-08-01 CN disclosed
CN-114106038-A Preparation method of hydroxyl phosphonate 浙江万盛股份有限公司 2022-03-01 CN disclosed
EP-3521364-B1 COPOLYMER COMPOSITION HAVING PHOSPHONATE GROUP KURARAY CO (JP) 2021-12-15 EP disclosed
EP-3521364-A1 COPOLYMER COMPOSITION HAVING PHOSPHONATE GROUP Kuraray Co., Ltd. (JP) 2019-08-07 EP disclosed
CN-102015035-B Composition and process for the destruction of organophosphorus and/or organosulphur pollutants ARKEMA FRANCE 2013-02-13 CN disclosed
EP-2271410-B1 COMPOSITION AND PROCESS FOR THE DESTRUCTION OF ORGANOPHOSPHORUS AND/OR ORGANOSULPHUR POLLUTANTS ARKEMA FRANCE (FR) 2011-10-12 EP disclosed
CN-102015035-A Composition and process for the destruction of organophosphorus and/or organosulphur pollutants ARKEMA FRANCE 2011-04-13 CN disclosed
EP-2271410-A2 COMPOSITION AND PROCESS FOR THE DESTRUCTION OF ORGANOPHOSPHORUS AND/OR ORGANOSULPHUR POLLUTANTS Arkema France (FR) 2011-01-12 EP disclosed
EP-1742642-A2 PHOSPHONATE ANALOGS OF HIV INTEGRASE INHIBITOR COMPOUNDS GILEAD SCIENCES, INC. (US) 2007-01-17 EP disclosed
US-20060217410-A1 Pre-organized tricyclic integrase inhibitor compounds GILEAD SCIENCES, INC. 2006-09-28 US disclosed
US-20060116356-A1 Phosphonate analogs of HIV integrase inhibitor compounds GILEAD SCIENCES, INC. 2006-06-01 US disclosed
WO-2005117904-A2 PHOSPHONATE ANALOGS OF HIV INTEGRASE INHIBITOR COMPOUNDS GILEAD SCIENCES, INC. (US) 2005-12-15 WO disclosed
EP-1558613-A2 PRE-ORGANIZED TRICYCLIC INTEGRASE INHIBITOR COMPOUNDS GILEAD SCIENCES, INC. (US) 2005-08-03 EP disclosed
US-20040167124-A1 Pre-organized tricyclic integrase inhibitor compounds GILEAD SCIENCES, INC. 2004-08-26 US disclosed
US-20040157804-A1 Pre-organized tricyclic integrase inhibitor compounds GILEAD SCIENCES, INC. 2004-08-12 US disclosed
WO-2004035577-A2 PRE-ORGANIZED TRICYCLIC INTEGRASE INHIBITOR COMPOUNDS GILEAD SCIENCES, INC. (US) 2004-04-29 WO disclosed
WO-2004035576-A2 PRE-ORGANIZED TRICYCLIC INTEGRASE INHIBITOR COMPOUNDS GILEAD SCIENCES, INC. (US) 2004-04-29 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060217410-A1 Pre-organized tricyclic integrase inhibitor compounds CCNI, INTS6, CCNE1 TSHR 3906/4885PPARD 4424/4885ALDH1A1 1113/4885
US-20040167124-A1 Pre-organized tricyclic integrase inhibitor compounds INTS6, INTS9, MUS81 TSHR 4025/4885PPARD 4259/4885ALDH1A1 2541/4885
US-20040157804-A1 Pre-organized tricyclic integrase inhibitor compounds INTS6, INTS9, MUS81 TSHR 4025/4885PPARD 4259/4885ALDH1A1 2541/4885
US-20060116356-A1 Phosphonate analogs of HIV integrase inhibitor compounds TYMP, PNP, PIKFYVE TSHR 4778/4885PPARD 4241/4885ALDH1A1 2788/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.