⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8173498 | 1.00 | — | — | |
| SCHEMBL16257999 | 0.75 | — | — | |
| SCHEMBL19380606 | 0.75 | — | — | |
| SCHEMBL18843050 | 0.75 | — | — | |
| SCHEMBL13880850 | 0.75 | — | — | |
| SCHEMBL8541897 | 0.75 | — | — | |
| SCHEMBL10672459 | 0.75 | — | — | |
| SCHEMBL7114404 | 0.71 | — | — | |
| SCHEMBL22139446 | 0.71 | — | — | |
| SCHEMBL20290530 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9969679-B2 | Anti-proliferative compounds and uses thereof | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2018-05-15 | — | — | US | disclosed |
| US-20170281773-A1 | BET BROMODOMAIN INHIBITORS AND THERAPEUTIC METHODS USING THE SAME | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-10-05 | — | — | US | disclosed |
| US-9675697-B2 | BET bromodomain inhibitors and therapeutic methods using the same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-06-13 | — | — | US | disclosed |
| US-9675697-B2 | BET bromodomain inhibitors and therapeutic methods using the same | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2017-06-13 | — | — | US | disclosed |
| US-20150191417-A1 | ANTI-PROLIFERATIVE COMPOUNDS AND USES THEREOF | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2015-07-09 | — | — | US | disclosed |
| US-8263735-B2 | Polymer compound and polymer light-emitting device using the same | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-09-11 | — | — | US | disclosed |
| US-20120008068-A1 | POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2012-01-12 | — | — | US | disclosed |
| US-20100133997-A1 | POLYMER COMPOUND AND POLYMER LIGHT-EMITTING DEVICE USING THE SAME | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-06-03 | — | — | US | disclosed |