Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 19/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | S1PR3 | Q99500 | 3/20 | 0.41 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1018972 | 0.94 | S1PR1 (0.52) | S1PR1S1PR3 | |
| SCHEMBL1015234 | 0.87 | S1PR1 (0.51) | S1PR1S1PR3 | |
| SCHEMBL12894422 | 0.87 | S1PR1 (0.49) | S1PR1CYP2C9S1PR3 | |
| SCHEMBL1201836 | 0.86 | S1PR1 (0.43) | S1PR1CYP2C9S1PR3 | |
| SCHEMBL1013921 | 0.86 | S1PR1 (0.58) | S1PR1S1PR3 | |
| Hydrochloric Acid SCHEMBL1014090 | 0.85 | S1PR1 (0.48) | S1PR1S1PR3 | |
| SCHEMBL1015055 | 0.85 | S1PR1 (0.49) | S1PR1CYP2C9S1PR3 | |
| SCHEMBL1015266 | 0.84 | S1PR1 (0.50) | S1PR1CYP2C9S1PR3 | |
| Hydrochloric Acid SCHEMBL1014089 | 0.79 | S1PR1 (0.56) | S1PR1S1PR3 | |
| SCHEMBL1014472 | 0.79 | S1PR1 (0.57) | S1PR1CYP2C9S1PR3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2271643-A1 | COMPOUNDS | Glaxo Group Limited (GB) | 2011-01-12 | — | — | EP | claimed |
| WO-2009133136-A1 | COMPOUNDS | GLAXO GROUP LIMITED (GB) | 2009-11-05 | — | — | WO | claimed |