Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 9/20 | 0.59 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.43 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.43 |
| ▸ | SLC9A3 | P48764 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | HTR2C | P28335 | 2/20 | 0.42 |
| ▸ | KHK | P50053 | 1/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22404799 | 0.89 | AVPR1A (0.66) | AVPR1ASLC9A3HTTHSD17B10ALDH1A1 | |
| SCHEMBL314441 | 0.85 | AVPR1A (0.58) | AVPR1ASLC9A3ALDH1A1KMT2A | |
| Hydrochloric Acid SCHEMBL314895 | 0.84 | AVPR1A (0.57) | AVPR1ASLC9A3ALDH1A1MEN1KMT2A | |
| SCHEMBL8357405 | 0.75 | AVPR1A (0.64) | AVPR1AHSD17B10ALDH1A1MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL5212234 | 0.74 | AVPR1A (0.62) | AVPR1AHSD17B10ALDH1A1HTR2CMEN1 | |
| SCHEMBL5010810 | 0.74 | AVPR1A (1.00) | AVPR1A | |
| SCHEMBL11086116 | 0.74 | AVPR1A (0.57) | AVPR1ASIGMAR1ALDH1A1CYP3A4MEN1 | |
| SCHEMBL10189974 | 0.74 | AVPR1A (0.57) | AVPR1AHTTHSD17B10ALDH1A1ALOX15 | |
| SCHEMBL21082454 | 0.73 | AVPR1A (0.50) | AVPR1ASLC9A3HTTHSD17B10ALDH1A1 | |
| SCHEMBL12362806 | 0.73 | AVPR1A (0.50) | AVPR1ASLC9A3HTTHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8093400-B2 | Compounds useful in therapy | PFIZER INC. (US) | 2012-01-10 | — | — | US | disclosed |
| US-20100317652-A1 | Compounds Useful In Therapy | PFIZER INC | 2010-12-16 | — | — | US | disclosed |
| US-7745630-B2 | Triazolyl piperidine arginine vasopressin receptor modulators | BRYANS JUSTIN STEPHEN | 2010-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100317652-A1 | Compounds Useful In Therapy | AVPR1A, AVPR1B, AVPR2 | AVPR1A 1/4885SLC18A3 358/4885SIGMAR1 364/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.