Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA1 | P30542 | 20/20 | 0.55 |
| ▸ | ADORA2B | P29275 | 4/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 6/20 | 0.48 |
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10194477 | 0.96 | ADORA1 (0.53) | ADORA1ADORA2BADORA2AADORA3 | |
| SCHEMBL382496 | 0.89 | ADORA1 (0.58) | ADORA1ADORA2BADORA2AADORA3 | |
| SCHEMBL10194562 | 0.88 | ADORA1 (0.51) | ADORA1ADORA2BADORA2AADORA3 | |
| SCHEMBL8030215 | 0.85 | ADORA1 (0.54) | ADORA1ADORA2BADORA2AADORA3 | |
| SCHEMBL8038927 | 0.85 | ADORA1 (0.46) | ADORA1ADORA2BADORA2AADORA3 | |
| SCHEMBL382755 | 0.83 | ADORA1 (0.55) | ADORA1ADORA2BADORA2AADORA3 | |
| SCHEMBL8034138 | 0.81 | ADORA1 (0.54) | ADORA1 | |
| SCHEMBL8032331 | 0.78 | ADORA1 (0.55) | ADORA1ADORA2BADORA2AADORA3 | |
| SCHEMBL8036775 | 0.78 | ADORA1 (0.55) | ADORA1ADORA2BADORA2AADORA3 | |
| SCHEMBL10194487 | 0.77 | ADORA1 (0.77) | ADORA1ADORA2BADORA2AADORA3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235011-B1 | SUBSTITUTED PYRROLO[2, 3-B]AND PYRAZOLO[3, 4-B]PYRIDINES FOR USE AS ADENOSINE RECEPTOR LIGANDS | Bayer Pharma AG (DE) | 2012-01-25 | — | — | EP | disclosed |