Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4B | Q07343 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 5/20 | 0.31 |
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.31 |
| ▸ | SCN7A | Q01118 | 1/20 | 0.30 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.30 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.30 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.30 |
| ▸ | ATF4 | P18848 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10254648 | 1.00 | PDE4B (0.32) | PDE4BSCN9ASCN10ASCN7AKCNH2 | |
| SCHEMBL10195450 | 0.88 | CYP1A2 (0.39) | — | |
| SCHEMBL10255136 | 0.88 | CYP1A2 (0.39) | — | |
| SCHEMBL10196187 | 0.86 | PDE4B (0.32) | PDE4BSCN9ASCN10ASCN7AKCNH2 | |
| SCHEMBL19071023 | 0.84 | MEN1 (0.32) | PDE4BSCN9ASCN10ASCN7AKCNH2 | |
| SCHEMBL10194959 | 0.84 | FFAR4 (0.36) | KCNH2 | |
| SCHEMBL10195581 | 0.82 | PPARG (0.35) | KCNH2 | |
| SCHEMBL10195194 | 0.81 | HTR2A (0.39) | KCNH2 | |
| SCHEMBL10195585 | 0.81 | EPHX2 (0.33) | KCNH2 | |
| SCHEMBL10196170 | 0.81 | PDE4B (0.34) | PDE4BSCN9ASCN7AKCNH2SCN5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20140378305-A1 | NOVEL HERBICIDES | SYNGENTA LIMITED (GB) | 2014-12-25 | — | — | US | disclosed |
| US-8865623-B2 | Herbicidally active cyclic diones and derivatives thereof, processes for their preparation, compositions, and method of controlling weeds | SYNGENTA LIMITED (GB) | 2014-10-21 | — | — | US | disclosed |
| US-20120021907-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20140378305-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | PDE4B 965/4885SCN9A 1880/4885SCN10A 2451/4885 |
| US-20120021907-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | PDE4B 1225/4885SCN9A 2224/4885SCN10A 1828/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.