SCHEMBL10195689

SCHEMBL10195689

CCc1c(F)c(F)c(C(F)(F)F)c(F)c1F

nearest known ligand 0.36

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.36
TSHR P16473 1/20 0.36
MEN1 O00255 1/20 0.32
KMT2A Q03164 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25644825 0.95 SMN1; SMN2 (0.34) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL25991367 0.90 TSHR (0.32) SMN1; SMN2TSHR
SCHEMBL10193866 0.80 SMN1; SMN2 (0.34) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL23848516 0.80 SMN1; SMN2 (0.35) SMN1; SMN2TSHRMEN1KMT2A
SCHEMBL23867626 0.80 TSHR (0.32) SMN1; SMN2TSHR
SCHEMBL12400893 0.80
SCHEMBL13185685 0.79
SCHEMBL29344192 0.77
SCHEMBL21653407 0.77
SCHEMBL25613890 0.77

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4270108-A1 CHEMICALLY AMPLIFIED POSITIVE RESIST COMPOSITION AND RESIST PATTERN FORMING PROCESS Shin-Etsu Chemical Co., Ltd. (JP) 2023-11-01 EP disclosed
EP-4198163-A1 METAL PATTERNING MATERIAL, AMINE COMPOUND, ELECTRONIC DEVICE, AND METHOD FOR FORMING METAL PATTERN Tosoh Corporation (JP) 2023-06-21 EP disclosed
US-20230026428-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES Beijing Summer Sprout Technology Co., Ltd. (CN) 2023-01-26 US disclosed
EP-4101835-A1 18F-SUBSTITUTED ESTERS OF CYCLOPROPANATED UNSATURATED FATTY ACIDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES Blanchette Rockefeller Neurosciences Institute (US) 2022-12-14 EP disclosed
EP-3567025-A1 HALOGENATED ESTERS OF CYCLOPROPANATED UNSATURATED FATTY ACIDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES Blanchette Rockefeller Neurosciences, Institute (US) 2019-11-13 EP disclosed
EP-3057934-B1 HALOGENATED ESTERS OF CYCLOPROPANATED UNSATURATED FATTY ACIDS FOR USE IN THE TREATMENT OF NEURODEGENERATIVE DISEASES BLANCHETTE ROCKEFELLER NEUROSCIENCES INST (US) 2019-03-27 EP disclosed
US-20120052685-A1 SILICON-CONTAINING FILM-FORMING COMPOSITION, SILICON-CONTAINING FILM-FORMED SUBSTRATE, AND PATTERNING PROCESS SHIN-ETSU CHEMICAL CO., LTD. (JP) 2012-03-01 US disclosed
WO-2011142359-A1 SPIRO COMPOUND AND DRUG FOR ACTIVATING ADIPONECTIN RECEPTOR 日産化学工業株式会社 (JP) 2011-11-17 WO disclosed
US-7244847-B2 Benzimidazole compounds ISIS PHARMACEUTICALS, INC. (US) 2007-07-17 US disclosed
US-7244847-B2 Benzimidazole compounds ISIS PHARMACEUTICALS, INC. (US) 2007-07-17 US disclosed
US-20070122738-A1 IMAGE FORMING MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 2007-05-31 US disclosed
US-20070122738-A1 IMAGE FORMING MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 2007-05-31 US disclosed
US-7160667-B2 Novolak phenolic resin, quaternary heterocyclic amine, and -onium or ammonium photo-thermal converting agents; positive planographic printing plate precursor; storage stability FUJI PHOTO FILM CO., LTD. (JP) 2007-01-09 US disclosed
US-7160667-B2 Novolak phenolic resin, quaternary heterocyclic amine, and -onium or ammonium photo-thermal converting agents; positive planographic printing plate precursor; storage stability FUJI PHOTO FILM CO., LTD. (JP) 2007-01-09 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230026428-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD1, OCIAD2, SLCO4C1 SMN1; SMN2 3530/4885TSHR 4433/4885MEN1 3949/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.