Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 12/20 | 0.42 |
| ▸ | PPARG | P37231 | 9/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL382955 | 0.91 | PPARA (0.42) | PPARAPPARGKDM4EALDH1A1LMNA | |
| SCHEMBL12910853 | 0.82 | PPARA (0.39) | PPARAPPARGKDM4EALDH1A1LMNA | |
| SCHEMBL8029952 | 0.82 | ADORA1 (0.43) | PPARAPPARGKDM4EALDH1A1LMNA | |
| SCHEMBL12163801 | 0.81 | PPARA (0.36) | PPARAPPARGKDM4EALDH1A1LMNA | |
| SCHEMBL10194194 | 0.79 | PPARA (0.37) | PPARAPPARGKDM4EALDH1A1LMNA | |
| SCHEMBL12163890 | 0.77 | ADORA1 (0.38) | PPARAPPARGKDM4EALDH1A1LMNA | |
| SCHEMBL1933429 | 0.75 | ADORA1 (0.43) | PPARAPPARGKDM4EALDH1A1MAPT | |
| SCHEMBL12164115 | 0.75 | ADORA1 (0.41) | KDM4EALDH1A1LMNAMAPT | |
| SCHEMBL10195768 | 0.74 | ADORA1 (0.57) | — | |
| SCHEMBL12163894 | 0.74 | ADORA1 (0.41) | KDM4EALDH1A1LMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2235011-B1 | SUBSTITUTED PYRROLO[2, 3-B]AND PYRAZOLO[3, 4-B]PYRIDINES FOR USE AS ADENOSINE RECEPTOR LIGANDS | Bayer Pharma AG (DE) | 2012-01-25 | — | — | EP | disclosed |