Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 3/20 | 0.37 |
| ▸ | PPARG | P37231 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 8/20 | 0.36 |
| ▸ | LTA4H | P09960 | 7/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.35 |
| ▸ | EGFR | P00533 | 4/20 | 0.35 |
| ▸ | BACE2 | Q9Y5Z0 | 2/20 | 0.34 |
| ▸ | IP6K1 | Q92551 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL19070614 | 1.00 | BACE1 (0.37) | BACE1PPARGBTKLTA4HKCNH2 | |
| SCHEMBL19070715 | 0.96 | BACE1 (0.36) | BACE1PPARGBTKLTA4HKCNH2 | |
| SCHEMBL13190200 | 0.96 | BACE1 (0.36) | BACE1PPARGBTKLTA4HKCNH2 | |
| SCHEMBL10196112 | 0.96 | BACE1 (0.36) | BACE1PPARGBTKLTA4HKCNH2 | |
| SCHEMBL10196259 | 0.91 | MAPK1 (0.44) | PPARGIP6K1 | |
| SCHEMBL19070882 | 0.91 | MAPK1 (0.44) | PPARGIP6K1 | |
| SCHEMBL10196296 | 0.89 | SCN9A (0.33) | BACE1 | |
| SCHEMBL10196314 | 0.89 | BACE1 (0.37) | BACE1PPARGBTKLTA4HKCNH2 | |
| SCHEMBL19070681 | 0.89 | BACE1 (0.37) | BACE1PPARGBTKLTA4HKCNH2 | |
| SCHEMBL19071475 | 0.89 | SCN9A (0.33) | BACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2389066-B1 | CYCLOPENTADIONE DERIVED HERBICIDES | SYNGENTA LTD (GB) | 2017-07-05 | — | — | EP | disclosed |
| US-8895474-B2 | Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds | SYNGENTA LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |
| US-8895474-B2 | Herbicidally active cyclopentanediones and derivatives thereof, and their use in controlling weeds | SYNGENTA LIMITED (GB) | 2014-11-25 | — | — | US | disclosed |
| US-20120021912-A1 | NOVEL HERBICIDES | SYNGENTA CROP PROTECTION LLC (US) | 2012-01-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120021912-A1 | NOVEL HERBICIDES | DDT, CYP4X1, CYP1B1 | BACE1 1901/4885PPARG 101/4885BTK 2749/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.