SCHEMBL1019609

SCHEMBL1019609

O=[N+]([O-])/C=C1\SCCCN1Cc1ccc(Cl)nc1

nearest known ligand 0.64

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CHRNA7 P36544 3/20 0.64
CHRNA1 P02708 2/20 0.64
CHRNA3 P32297 1/20 0.64
SMN1; SMN2 Q16637 1/20 0.61
CHRNB2 P17787 2/20 0.56
CHRNA4 P43681 2/20 0.56
ALDH1A1 P00352 2/20 0.51
CYP3A4 P08684 1/20 0.51
CYP2D6 P10635 1/20 0.51
MAPT P10636 1/20 0.51
CYP2C9 P11712 1/20 0.51
CYP2C19 P33261 1/20 0.51
RXFP1 Q9HBX9 1/20 0.51
CASP6 P55212 1/20 0.47
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
TDP1 Q9NUW8 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1019610 1.00 CHRNA7 (0.64) CHRNA7CHRNA1CHRNA3SMN1; SMN2CHRNB2
SCHEMBL10026156 0.93 SMN1; SMN2 (0.64) CHRNA7CHRNA1CHRNA3SMN1; SMN2CHRNB2
SCHEMBL1020000 0.93 SMN1; SMN2 (0.64) CHRNA7CHRNA1CHRNA3SMN1; SMN2CHRNB2
SCHEMBL1020001 0.93 SMN1; SMN2 (0.64) CHRNA7CHRNA1CHRNA3SMN1; SMN2CHRNB2
SCHEMBL9070398 0.86 CHRNA7 (0.47) CHRNA7CHRNA1CHRNA3SMN1; SMN2CHRNB2
SCHEMBL7996219 0.86 CHRNA1 (0.47) CHRNA7CHRNA1CHRNA3SMN1; SMN2CHRNB2
SCHEMBL9070394 0.86 CHRNA1 (0.47) CHRNA7CHRNA1CHRNA3SMN1; SMN2CHRNB2
SCHEMBL7993705 0.86 CHRNA7 (0.47) CHRNA7CHRNA1CHRNA3SMN1; SMN2CHRNB2
SCHEMBL9070391 0.86 CHRNA7 (0.47) CHRNA7CHRNA1CHRNA3SMN1; SMN2CHRNB2
SCHEMBL7993655 0.86 CHRNA7 (0.47) CHRNA7CHRNA1CHRNA3SMN1; SMN2CHRNB2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 40 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20010051643-A1 Agents for preserving technical materials against insects TSUBOI SHINICHI (JP) 2001-12-13 US claimed
US-5428032-A Insecticides NIHON BAYER AGROCHEM K.K. (JP) 1995-06-27 US claimed
EP-0431361-B1 Use of stabilizers for agrochemical compositions BAYER AGROCHEM KK (JP) 1994-02-23 EP claimed
EP-0431362-B1 Stabilized agrochemical compositions BAYER AGROCHEM KK (JP) 1993-11-03 EP claimed
EP-0511541-A1 Agents for preserving wood or composite-wood materials against insects NIHON BAYER AGROCHEM K.K. (JP) 1992-11-04 EP claimed
EP-0431361-A1 Use of stabilizers for agrochemical compositions NIHON BAYER AGROCHEM K.K. (JP) 1991-06-12 EP claimed
EP-0431362-A1 Stabilized agrochemical compositions NIHON BAYER AGROCHEM K.K. (JP) 1991-06-12 EP claimed
US-12207644-B2 Insect barrier ENGINEERED MATERIALS, INC. (US) 2025-01-28 US disclosed
US-11291199-B2 Insect barrier ENGINEERED MATERIALS, INC. (US) 2022-04-05 US disclosed
US-20210161121-A1 INSECT BARRIER ENGINEERED MATERIALS, INC. (US) 2021-06-03 US disclosed
US-20160158960-A1 IRON-CORROSION INHIBITION METHOD, AND WOOD TREATMENT METHOD KATAYAMA CHEMICAL INC. (JP) 2016-06-09 US disclosed
WO-2016081184-A1 INSECT BARRIER ENGINEERED MATERIALS, INC. (US) 2016-05-26 WO disclosed
US-20160135443-A1 INSECT BARRIER ENGINEERED MATERIALS, INC. (US) 2016-05-19 US disclosed
EP-0511541-A1 Agents for preserving wood or composite-wood materials against insects NIHON BAYER AGROCHEM K.K. (JP) 1992-11-04 EP disclosed
US-5140019-A Mixtures of substituted imidazolines and organophosphorus compounds with polyether stabilizers NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1992-08-18 US disclosed
EP-0431361-A1 Use of stabilizers for agrochemical compositions NIHON BAYER AGROCHEM K.K. (JP) 1991-06-12 EP disclosed
EP-0431362-A1 Stabilized agrochemical compositions NIHON BAYER AGROCHEM K.K. (JP) 1991-06-12 EP disclosed
EP-0256407-B1 INSECTICIDAL AGENT NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1991-03-06 EP disclosed
US-4845106-A INSECTICIDES NIHON TOKUSHU NOYAKU SEIZO K.K. (JP) 1989-07-04 US disclosed
EP-0192060-A1 Heterocyclic compounds NIHON BAYER AGROCHEM K.K. (JP) 1986-08-27 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20010051643-A1 Agents for preserving technical materials against insects GPX1, FEN1, POT1 CHRNA7 4679/4885CHRNA1 4520/4885CHRNA3 4790/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.