SCHEMBL1019645

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1018684	0.93	HSP90AA1 (0.75)	HSP90AA1HSP90AB1HSP90B1HDAC8HDAC3
	SCHEMBL1019255	0.93	HSP90AB1 (0.66)	HSP90AA1HSP90AB1HSP90B1HDAC8HDAC3
	SCHEMBL1020329	0.91	HSP90AA1 (0.80)	HSP90AA1HSP90AB1HSP90B1HDAC8HDAC3
	SCHEMBL1019466	0.88	HSP90AA1 (0.73)	HSP90AA1HSP90AB1HSP90B1HDAC8HDAC3
	SCHEMBL3376947	0.87	HSP90AA1 (0.76)	HSP90AA1HSP90AB1HSP90B1HDAC8HDAC3
	Onalespib SCHEMBL382780	0.86	HSP90AA1 (1.00)	HSP90AA1HSP90AB1HSP90B1HDAC8HDAC3
	Onalespib SCHEMBL29351356	0.86	HSP90AA1 (1.00)	HSP90AA1HSP90AB1HSP90B1HDAC8HDAC3
	SCHEMBL13309168	0.86	HSP90AA1 (0.75)	HSP90AA1HSP90AB1HSP90B1HDAC8HDAC3
	SCHEMBL1018432	0.85	HSP90AA1 (0.80)	HSP90AA1HSP90AB1HSP90B1HDAC8HDAC3
	SCHEMBL1019009	0.85	HSP90AA1 (0.74)	HSP90AA1HSP90AB1HSP90B1HDAC8HDAC3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.