SCHEMBL1019703

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1021339	0.86	KDM4E (0.49)	MAPTHPGDHSD17B10POLBTSHR
	SCHEMBL382778	0.86	HPGD (0.55)	MAPTHPGDHSD17B10POLBTSHR
	SCHEMBL1018553	0.85	HTT (0.47)	MAPTHPGDHSD17B10POLBTSHR
	SCHEMBL1019840	0.83	EGFR (0.39)	MAPTHPGDHSD17B10POLBTSHR
	SCHEMBL1038769	0.81	HTT (0.70)	MAPTHPGDHSD17B10HTTHMGCR
	SCHEMBL28252586	0.81	HTT (0.70)	MAPTHPGDHSD17B10HTTHMGCR
	SCHEMBL18677495	0.80	HSP90AA1 (0.53)	MAPTTSHRLMNACYP3A4PTGS2
	SCHEMBL20724883	0.80	HTT (0.57)	MAPTHPGDHSD17B10HTTHMGCR
	SCHEMBL29924059	0.80	HSP90AA1 (0.53)	MAPTTSHRLMNACYP3A4PTGS2
	SCHEMBL3836141	0.80	MAPT (0.64)	MAPTHPGDHSD17B10TSHRHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.