Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | NPC1 | O15118 | 4/20 | 0.55 |
| ▸ | RAB9A | P51151 | 4/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | HTR2C | P28335 | 2/20 | 0.47 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | P2RX1 | P51575 | 1/20 | 0.46 |
| ▸ | P2RX3 | P56373 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | HTR1A | P08908 | 1/20 | 0.44 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11545254 | 0.90 | MEN1 (0.56) | KMT2AMEN1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL6827246 | 0.85 | MEN1 (0.61) | KMT2AMEN1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL2673587 | 0.84 | KMT2A (0.56) | KMT2AMEN1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL3919116 | 0.83 | MEN1 (0.55) | KMT2AMEN1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL11613000 | 0.83 | MEN1 (0.55) | KMT2AMEN1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL22075574 | 0.83 | KMT2A (0.55) | KMT2AMEN1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL29220951 | 0.82 | MEN1 (0.54) | KMT2AMEN1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL3151804 | 0.82 | KMT2A (0.54) | KMT2AMEN1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL18204368 | 0.82 | MEN1 (0.54) | KMT2AMEN1NPSR1SMN1; SMN2NPC1 | |
| SCHEMBL9217126 | 0.81 | KMT2A (0.56) | KMT2AMEN1NPSR1SMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116789636-A | Bifunctional compound, preparation method, pharmaceutical composition and application thereof | 北京康辰药业股份有限公司 | 2023-09-22 | — | — | CN | disclosed |
| WO-2011044538-A9 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2012-01-05 | — | — | WO | disclosed |
| WO-2011044538-A1 | ANTIBACTERIAL AMINOGLYCOSIDE ANALOGS | ACHAOGEN, INC. (US) | 2011-04-14 | — | — | WO | disclosed |
| EP-0001280-B1 | 1-N-ACYLATED-4-O-GLYCOSYL-6-O-GLYCOSYL-1,3-DIAMINOCYCLITOL DERIVATIVES, PROCESS FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SHIONOGI & CO., LTD. (JP) | 1981-11-25 | — | — | EP | disclosed |
| US-4199570-A | AZETIDINE, PYRROLIDINE, OR PIPERIDINE | SHIONOGI & CO., LTD. (JP) | 1980-04-22 | — | — | US | disclosed |
| EP-0001280-A2 | 1-N-acylated-4-O-glycosyl-6-O-glycosyl-1,3-diaminocyclitol derivatives, process for their preparation and pharmaceutical compositions containing them | SHIONOGI & CO., LTD. (JP) | 1979-04-04 | — | — | EP | disclosed |