Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GCK | P35557 | 17/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 2/20 | 0.40 |
| ▸ | CCR6 | P51684 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2658925 | 0.90 | GCK (0.49) | GCKADORA2A | |
| SCHEMBL2656137 | 0.88 | GCK (0.52) | GCKADORA2A | |
| SCHEMBL2655247 | 0.80 | GCK (0.65) | GCKCCR6 | |
| SCHEMBL2656198 | 0.80 | GCK (0.50) | GCKADORA2A | |
| SCHEMBL2657658 | 0.80 | GCK (0.53) | GCKADORA2A | |
| SCHEMBL2655933 | 0.79 | GCK (0.49) | GCKADORA2A | |
| SCHEMBL2655447 | 0.79 | GCK (0.53) | GCKADORA2A | |
| SCHEMBL2656202 | 0.79 | GCK (0.49) | GCKADORA2A | |
| SCHEMBL11972500 | 0.74 | GCK (0.68) | GCK | |
| SCHEMBL2655672 | 0.73 | BRD4 (0.49) | GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2125735-B1 | 2,2,2-TRI-SUBSTITUTED ACETAMIDE DERIVATIVES AS GLUCOKINASE ACTIVATORS, THEIR PROCESS AND PHARMACEUTICAL APPLICATION | ADVINUS THERAPEUTICS PRIVATE LTD (IN) | 2012-06-27 | — | — | EP | disclosed |