Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN9A | Q15858 | 19/20 | 0.46 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.43 |
| ▸ | SCN2B | O60939 | 1/20 | 0.43 |
| ▸ | SCN1A | P35498 | 1/20 | 0.43 |
| ▸ | SCN1B | Q07699 | 1/20 | 0.43 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15094313 | 0.87 | SCN9A (0.46) | SCN9ASCN5ASCN2BSCN1ASCN1B | |
| SCHEMBL363186 | 0.85 | SCN9A (0.46) | SCN9ASCN5A | |
| SCHEMBL10198138 | 0.84 | SCN9A (0.44) | SCN9ASCN5ASCN2BSCN1ASCN1B | |
| Lithium SCHEMBL364790 | 0.84 | SCN9A (0.46) | SCN9ASCN5A | |
| SCHEMBL364788 | 0.84 | SCN9A (0.46) | SCN9ASCN5A | |
| SCHEMBL16175148 | 0.83 | SCN9A (0.47) | SCN9ASCN5A | |
| SCHEMBL365758 | 0.82 | SCN9A (0.55) | SCN9ASCN5A | |
| SCHEMBL371347 | 0.80 | SCN9A (0.64) | SCN9ASCN5A | |
| SCHEMBL15543236 | 0.79 | SCN9A (0.67) | SCN9ASCN5ASCN2BSCN1ASCN1B | |
| SCHEMBL363968 | 0.79 | SCN9A (0.55) | SCN9ASCN5ASCN2BSCN1ASCN1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120010183-A1 | Chemical Compounds | PFIZER LIMITED (GB) | 2012-01-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120010183-A1 | Chemical Compounds | SCN1A, SCN1B, SCN7A | SCN9A 25/4885SCN5A 4/4885SCN2B 22/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.