Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCN10A | Q9Y5Y9 | 2/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13221474 | 1.00 | SCN10A (0.32) | SCN10ANPC1RAB9ANPY5R | |
| SCHEMBL13087621 | 0.94 | — | — | |
| SCHEMBL14641545 | 0.89 | — | — | |
| SCHEMBL13221478 | 0.89 | — | — | |
| SCHEMBL883267 | 0.87 | — | — | |
| SCHEMBL12404445 | 0.86 | AAK1 (0.40) | SCN10ANPC1RAB9ANPY5R | |
| SCHEMBL12373600 | 0.86 | TYMS (0.33) | — | |
| SCHEMBL10200241 | 0.86 | TYMS (0.33) | — | |
| SCHEMBL16229728 | 0.83 | — | — | |
| SCHEMBL19488499 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2398794-B1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL MYERS SQUIBB CO (US) | 2013-01-16 | — | — | EP | disclosed |
| WO-2012018325-A1 | HEPATITIS C VIRUS INHIBITORS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2012-02-09 | — | — | WO | disclosed |