SCHEMBL10202000

SCHEMBL10202000

Cc1ccc2c(c1)/C(=C/c1ccc(N(C)C)cc1)C(=O)N2C

nearest known ligand 0.70

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
MAPT P10636 9/20 0.70
APP P05067 7/20 0.70
SNCA P37840 6/20 0.70
ERBB2 P04626 1/20 0.48
NOX4 Q9NPH5 1/20 0.47
NOX1 Q9Y5S8 1/20 0.47
MEN1 O00255 3/20 0.46
KMT2A Q03164 3/20 0.46
NPC1 O15118 1/20 0.46
RAB9A P51151 1/20 0.46
GPR35 Q9HC97 1/20 0.46
METAP1 P53582 1/20 0.43
PDGFRB P09619 1/20 0.43
ALDH1A1 P00352 2/20 0.43
GAA P10253 1/20 0.43
CRHBP P24387 1/20 0.43
CRHR2 Q13324 1/20 0.43
PIM1 P11309 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14589620 0.84 MAPT (0.55) MAPTAPPSNCAMEN1KMT2A
SCHEMBL6001665 0.82 MAPT (1.00) MAPTAPPSNCAERBB2MEN1
SCHEMBL14589616 0.82 MAPT (1.00) MAPTAPPSNCAERBB2MEN1
SCHEMBL14589623 0.76 MAPT (0.55) MAPTAPPSNCAMEN1KMT2A
SCHEMBL125194 0.75 MAPT (0.64) MAPTAPPSNCANOX4NOX1
SCHEMBL10205375 0.71 CA1 (0.50) MAPTAPPMEN1KMT2AALDH1A1
SCHEMBL14198800 0.71 MAPT (0.63) MAPTAPPSNCAMEN1KMT2A
SCHEMBL13819617 0.69 TLK2 (0.42) MAPTNPC1RAB9APDGFRBPIM1
SCHEMBL14589624 0.69 APP (0.62) MAPTAPPSNCAALDH1A1
SCHEMBL14589625 0.68 MAPT (0.58) MAPTAPPSNCAMEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1744212-B1 Photosensitive composition FUJIFILM CORP (JP) 2012-01-11 EP disclosed
EP-1744212-A2 Photosensitive composition Fuji Photo Film Co., Ltd. (JP) 2007-01-17 EP disclosed