⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6983611 | 0.80 | MEN1 (0.31) | — | |
| SCHEMBL10740777 | 0.79 | — | — | |
| SCHEMBL11744095 | 0.79 | — | — | |
| SCHEMBL10207658 | 0.78 | — | — | |
| SCHEMBL11744564 | 0.76 | — | — | |
| SCHEMBL10207632 | 0.76 | — | — | |
| SCHEMBL11443853 | 0.75 | — | — | |
| SCHEMBL21786390 | 0.74 | — | — | |
| SCHEMBL11464468 | 0.74 | CYP1A2 (0.44) | — | |
| SCHEMBL8595121 | 0.74 | EPHX1 (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115465913-B | Activated carbon multistage adding method for enhancing removal of micro-pollutants in water | 中国科学院生态环境研究中心 | 2023-03-24 | — | — | CN | claimed |
| CN-115465913-A | Activated carbon multistage adding method for enhancing removal of micro-pollutants in water | 中国科学院生态环境研究中心 | 2022-12-13 | — | — | CN | claimed |
| US-11833137-B2 | Substituted chromenones, IRE1 inhibitors, and methods of using same | THE WISTAR INSTITUTE (US) | 2023-12-05 | — | — | US | disclosed |
| US-20230183164-A1 | Synthesis of Vinyl Cyclobutyl Intermediates | AMGEN INC. (US) | 2023-06-15 | — | — | US | disclosed |
| US-20230174496-A1 | Synthesis of Vinylic Protected Alcohol Intermediates | AMGEN INC. (US) | 2023-06-08 | — | — | US | disclosed |
| US-20230174496-A1 | Synthesis of Vinylic Protected Alcohol Intermediates | AMGEN INC. (US) | 2023-06-08 | — | — | US | disclosed |
| CN-115465913-B | Activated carbon multistage adding method for enhancing removal of micro-pollutants in water | 中国科学院生态环境研究中心 | 2023-03-24 | — | — | CN | disclosed |
| CN-115465913-A | Activated carbon multistage adding method for enhancing removal of micro-pollutants in water | 中国科学院生态环境研究中心 | 2022-12-13 | — | — | CN | disclosed |
| WO-2021226009-A1 | SYNTHESIS OF VINYL CYCLOBUTYL INTERMEDIATES | AMGEN INC. (US) | 2021-11-11 | — | — | WO | disclosed |
| EP-3414238-B1 | SUBSTITUTED IMIDAZOLYL-CARBOXAMIDES AS PESTICIDES | BAYER CROPSCIENCE AG (DE) | 2021-03-24 | — | — | EP | disclosed |
| US-20210008043-A1 | Substituted Chromenones, IRE1 Inhibitors, and Methods of Using Same | NATIONAL INSTITUTES OF HEALTH | 2021-01-14 | — | — | US | disclosed |
| US-7501508-B2 | Methods and intermediates for the synthesis of porphyrins | NORTH CAROLINE STATE UNIVERSITY (US) | 2009-03-10 | — | — | US | disclosed |
| US-7501508-B2 | Methods and intermediates for the synthesis of porphyrins | NORTH CAROLINE STATE UNIVERSITY (US) | 2009-03-10 | — | — | US | disclosed |
| US-7425634-B2 | Benzimidazole compound | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2008-09-16 | — | — | US | disclosed |
| US-20070027311-A1 | Methods and intermediates for the synthesis of porphyrins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-01 | — | — | US | disclosed |
| US-20070027311-A1 | Methods and intermediates for the synthesis of porphyrins | NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT | 2007-02-01 | — | — | US | disclosed |
| US-20070015782-A1 | Benzimidazole compound | EISAI CO., LTD. | 2007-01-18 | — | — | US | disclosed |
| US-20070015782-A1 | Benzimidazole compound | EISAI CO., LTD. | 2007-01-18 | — | — | US | disclosed |
| US-20070010542-A1 | Benzimidazole compound | EISAI CO., LTD. | 2007-01-11 | — | — | US | disclosed |
| US-4324921-A | CATALYTIC ISOMERIZATION OF 5,5-DIMETHYL-1,3-DIOXANS | HOECHST AKTIENGESELLSCHAFT (DE) | 1982-04-13 | — | — | US | disclosed |