Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 12/20 | 0.89 |
| ▸ | ALK | Q9UM73 | 7/20 | 0.82 |
| ▸ | IGF1R | P08069 | 7/20 | 0.60 |
| ▸ | INSR | P06213 | 6/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL517813 | 0.94 | EGFR (0.86) | EGFRALKIGF1RINSRKCNH2 | |
| SCHEMBL30341887 | 0.94 | EGFR (1.00) | EGFRALKIGF1RINSR | |
| SCHEMBL517288 | 0.94 | EGFR (1.00) | EGFRALKIGF1RINSR | |
| SCHEMBL517278 | 0.92 | EGFR (0.85) | EGFRALKIGF1RINSR | |
| SCHEMBL517458 | 0.91 | EGFR (0.82) | EGFRALKIGF1RINSRKCNH2 | |
| SCHEMBL518078 | 0.91 | EGFR (0.83) | EGFRALKIGF1RINSR | |
| SCHEMBL517382 | 0.91 | EGFR (0.81) | EGFRALKIGF1RINSRKCNH2 | |
| SCHEMBL574464 | 0.91 | EGFR (0.81) | EGFRALKIGF1RINSRKCNH2 | |
| SCHEMBL29355191 | 0.90 | ALK (1.00) | EGFRALKIGF1RKCNH2 | |
| SCHEMBL517412 | 0.90 | ALK (1.00) | EGFRALKIGF1RKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012017239-A2 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2012-02-09 | — | — | WO | disclosed |